BMS 270: Advances in understanding humoral immunity in humans
Spring 2016 module 1 minicourse
Course director: Jason Cyster
Other faculty: Bryan Greenhouse
Days/times: MTWThF 2-4pm, 4/4-4/15/16
Campus: PH
Room: S-176
Description: The convergence of advances in isolating single antigen-reactive B cells and in deep sequencing of immunoglobulin (Ig) genes has led to remarkable insights into the properties and dynamics of human antibody responses. Through a series of discussion papers, this minicourse will review the current technologies used for tracking human B cell responses while teaching about the advances that have been made in understanding human broadly neutralizing antibody responses against HIV-1 and influenza virus; the B cell response against malaria; and B cell responses occurring in autoimmune disease. The minicourse will provide an opportunity to reinforce your knowledge about antibodies, and about germinal center, plasma cell and memory B cell responses, relationships between disease epidemiology and humoral immunity, and it will discuss findings that are guiding efforts to develop vaccines capable of inducing broadly neutralizing antibodies against viruses.
- Instructor: Jason Cyster
- Instructor: Bryan Greenhouse
- Instructor: Demian Sainz