Section outline

  • Lecture: Discussion Seminar: Use of biomarkers in clinical development
    The use of diagnostic biomarkers and surrogate biomarkers in drug development will be covered. Review of case studies of how these different types of biomarkers have been utilized in drug development.

    Faculty: June Lee

    Location:     China Basin 6702

    • Session Slides:

    • Biomarker Lecture 2012 Final File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Buyse M, Michiels S, Sargent DJ, Grothey A, Matheson A, de Gramont A. Integrating biomarkers in clinical trials. Expert Rev Mol Diagn. 2011 Mar;11(2):171-82. File
    • Frank R, Hargreaves R. Clinical biomarkers in drug discovery and development File
      Not available unless: Your ID number contains 02

    • Assignment:  Case reports are due on June 4th.  Please email a copy of your case report to Janel Long-Boyle before coming to the class discussion.