Section outline

  • Confounding and Interaction III: Stratified Analysis

    Concept of weighted averages; use of stratification to form adjusted measures; managing multiple confounding paths; software implementation to detect minimally sufficient set for adjustment; limitations of stratification including time-dependent confounding/mediation

    Faculty:  Jeffrey Martin

    • Lecture Slides:

    • Confounding and Interaction III 2021 File

    • Lecture Audio/Video Recording (Access restricted to registered students): 

    • Watch 2021 URL
      Not available unless: You belong to a group in Registered Students Only

    • Large Group Discussion (Access restricted to registered students):
      Brief formal review of lecture followed by question and answer discussion. Recorded lecture should be viewed prior to this session.

    • Watch 2021 Media Resource
      Not available unless: You belong to Registered Students Only

    • Recommended Reading:

      S & N: Ch. 7: sections 7.1 - 7.2.1 and sections 7.3.3 - 7.3.4

      dagitty.net, an open source browser-based environment for creating, editing, and analyzing directed acyclic graphs

    • Optional Reading:

    • Shrier I and Platt R. Reducing bias through directed acyclic graphs. BMC Medical Research Methodology 8:70, 2008. File
      Not available unless: Your ID number contains 02
    • Suarez D et al. Differences between marginal structural models and conventional models in their exposure effect estimates. Epidemiology 22: 586-588, 2011. File
      Not available unless: Your ID number contains 02
    • Greenland S and Pearce N Statistical Foundations for Model Based Adjustments Ann Rev Pub Health 2015 File
      Not available unless: Your ID number contains 02
    • Myers et al Effects of adjusting for instrumental variables on bias and precision of effect estimates AJE 174 11 1213 2011 File
      Not available unless: Your ID number contains 02
    • VanderWeele et al Sensitivity Analysis Obs Research E-Value Ann Intern Med 2017 File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 11

    • Problem Set 11 Confounding and Interaction III 2021 File
    • esophageal cancer File

    • Assignment Due Date:  December 7, 2021 at the beginning of Small Group Section

    • Assignment Answer Key (Access restricted to registered students):

    • Problem Set 11 Confounding and Interaction III 2021 Answer Key File
    • Problem Set 11 Confounding and Interaction III 2021 Answer Key File