Section outline

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  • Monday, January 4, 2016; 1:00 PM - 3:00 PM

    Lecture: Introduction to NTDs and vector-borne diseases

    Introduction to NTDS, basics of vector-borne transmission

    Faculty:  Caryn Bern, Roly Gosling, Jimee Hwang

    Location:  Mission Hall 1109

    • Prospectus:

    • Required Reading:

    • Yamey G, Torreele E. The world's most neglected diseases. BMJ 2002;325:176-7. File
      Not available unless: Your ID number contains 02
    • Ribeiro J.M.C., Valenzuela J.G. Vector Biology In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. Edinburgh, Scotland: Churchill Livingstone Elsevier; 2011:45-51. File
      Not available unless: Your ID number contains 02
    • Hotez PJ, Molyneux DH, Fenwick A, Kumaresan J, Sachs SE, Sachs JD, Savioli L. Control of neglected tropical diseases. N Engl J Med. 2007 Sep 6;357(10):1018-27. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

      Warrell D, Gilles H. Essential Malariology 4th ed. 2002: 73-78

    • Pates H, Curtis C. Mosquito behaviour and vector control. Annu Rev Entomol 2005: 50: 53–70 File
      Not available unless: Your ID number contains 02
    • Smith DL, Perkins TA, Reiner RC Jr et al. Recasting the theory of mosquito-borne pathogen transmission dynamics and control. Trans R Soc Trop Med Hyg. 2014 Apr;108(4):185-97. File
      Not available unless: Your ID number contains 02
    • World Health Organization. First WHO report on neglected tropical diseases: working to overcome the global impact of neglected tropical diseases. WHO/HTM/NTD/2010.1. File
      Not available unless: Your ID number contains 02

    • Assignment:

       

    • Article review/discussion sign-up Forum

      Please use the forum to post your date preference.

      Date

      Article review/discussion

      Student sign-up

      1/12/2015

      Leishmaniasis

      1/26/2015

      Chagas disease

      2/2/2015

      Trachoma 

      2/9/2015

      Arboviruses

      2/23/2015

      Malaria 

      3/2/2015

      Schistosomiasis 

  • Monday, January 11, 2016; 1:00 PM - 3:00 PM

    Lecture: Leishmaniasis

    Faculty:  Caryn Bern

    Location:  Mission Hall 1109

    • Session Slides:

    • Required Reading:

    • Jeronimo SMB, de Queiroz Sousa A, Pearson RD. Leishmaniasis. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. Edinburgh, Scotland: Churchill Livingstone Elsevier; 2011:696-706. File
      Not available unless: Your ID number contains 02
    • Bern C, Courtenay O, Alvar J. Of cattle, sand flies and men: a systematic review of risk factor analyses for South Asian visceral leishmaniasis and implications for elimination. PLoS Negl Trop Dis. 2010 Feb 9;4(2):e599. File
      Not available unless: Your ID number contains 02
    • Picado A, Singh SP, Rijal S, et al. Longlasting insecticidal nets for prevention of Leishmania donovani infection in India and Nepal: paired cluster randomised trial. BMJ 2010;341:c6760. File
      Not available unless: Your ID number contains 02
    • Mondal D, Huda MM, Karmoker MK, et al. Reducing visceral leishmaniasis by insecticide impregnation of bed-nets, Bangladesh. Emerg Infect Dis 2013;19:1131-4. File
      Not available unless: Your ID number contains 02
    • Chowdhury R, Huda MM, Kumar V, et al. The Indian and Nepalese programmes of indoor residual spraying for the elimination of visceral leishmaniasis: performance and effectiveness. Annals of tropical medicine and parasitology 2011;105:31-5. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Alvar J, Velez ID, Bern C, et al. Leishmaniasis worldwide and global estimates of its incidence. PloS one 2012;7:e35671. File
      Not available unless: Your ID number contains 02
    • Alvar J, Yactayo S, Bern C. Leishmaniasis and poverty. Trends Parasitol 2006;22:552-7. File
      Not available unless: Your ID number contains 02
    • World Health Organization. Control of the leishmaniases. World Health Organ Tech Rep Ser 2010: 1-186. File
      Not available unless: Your ID number contains 02

  • Monday, January 18, 2016; No Class - MLK Holiday

  • Monday, January 25, 2016; 1:00 PM - 3:00 PM

    Lecture: Chagas disease

    Faculty:  Caryn Bern

    Location:  Mission Hall 1109

    • Session Slides:

    • Required Reading:

    • Rassi A, Jr., Rassi A, Marin-Neto JA. Chagas disease. Lancet 2010;375:1388-402. File
      Not available unless: Your ID number contains 02
    • Gurtler RE. Sustainability of vector control strategies in the Gran Chaco Region: current challenges and possible approaches. Memorias do Instituto Oswaldo Cruz 2009;104 Suppl 1:52-9. File
      Not available unless: Your ID number contains 02
    • Abad-Franch F, Diotaiuti L, Gurgel-Goncalves R, Gurtler RE. Certifying the interruption of Chagas disease transmission by native vectors: cui bono? Mem Inst Oswaldo Cruz 2013;108:251-4. File
      Not available unless: Your ID number contains 02
    • Feliciangeli MD, Campbell-Lendrum D, Martinez C, Gonzalez D, Coleman P, Davies C. Chagas disease control in Venezuela: lessons for the Andean region and beyond. Trends Parasitol 2003;19:44-9. File
      Not available unless: Your ID number contains 02
    • Samuels AM, Clark EH, Galdos-Cardenas G, et al. Epidemiology of and impact of insecticide spraying on Chagas disease in communities in the Bolivian Chaco. PLoS Negl Trop Dis 2013;7:e2358. File
      Not available unless: Your ID number contains 02
    • Bowman NM, Kawai V, Levy MZ, et al. Chagas disease transmission in periurban communities of Arequipa, Peru. Clin Infect Dis 2008;46:1822-8. File
      Not available unless: Your ID number contains 02
    • Delgado S, Castillo Neyra R, Quispe Machaca VR, et al. A history of chagas disease transmission, control, and re-emergence in peri-rural La Joya, Peru. PLoS Negl Trop Dis 2011;5:e970. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Clark EH, Sherbuk J, Okamoto E, et al. Hyperendemic Chagas disease and the unmet need for pacemakers in the Bolivian Chaco. PLoS Negl Trop Dis 2014;8:e2801. File
      Not available unless: Your ID number contains 02
    • Molina I, Gomez i Prat J, Salvador F, et al. Randomized trial of posaconazole and benznidazole for chronic Chagas' disease. N Engl J Med 2014;370:1899-908. File
      Not available unless: Your ID number contains 02

  • Monday, February 1, 2016; 1:00 PM - 3:00 PM

    Lecture: Trachoma

    Faculty:  Thomas Lietman

    Location:  Mission Hall 1109

    • Session Slides:

    • Required Reading:

    • Taylor HR, Burton MJ, Haddad D, West S, Wright H. Lancet. 2014 Jul 16. File
      Not available unless: Your ID number contains 02
    • Azithromycin in control of trachoma. Schachter J, West SK, Mabey D, Dawson CR, Bobo L, Bailey R, Vitale S, Quinn TC, Sheta A, Sallam S, Mkocha H, Mabey D, Faal H. Lancet. 1999 Aug 21;354(9179):630-5. File
      Not available unless: Your ID number contains 02
    • Is Credé’s prophylaxis for ophthalmia neonatorum still valid. Schaller UC and Klauss V. Bulletin of the WHO, 2001. 79 (3) 262-263. (Or if someone wants the original German: Die Verhutüng der Augenentzündung der Neugeborenen. Credé CSF. Arhiv für Gynaekolo File
      Not available unless: Your ID number contains 02
    • Crede 1881 File
      Not available unless: Your ID number contains 02
    • Impact of mass treatment of onchocerciasis with ivermectin on the transmission of infection. Taylor HR, Pacqué M, Muñoz B, Greene BM. Science. 1990 Oct 5;250(4977):116-8. File
      Not available unless: Your ID number contains 02
    • Impact of vitamin A supplementation on childhood mortality. A randomised controlled community trial. Sommer A, Tarwotjo I, Djunaedi E, West KP Jr, Loeden AA, Tilden R, Mele L. Lancet. 1986 May 24;1(8491):1169-73. File
      Not available unless: Your ID number contains 02

  • Monday, February 8, 2016; 1:00 PM - 3:00 PM

    Lecture: Arboviruses

    Faculty:  Angelle Desiree LaBeaud

    Location:  Mission Hall 1109

    • Session Slides:

    • Weaver and Reisen. Present and Future Arboviral Threats. Antiviral Research. Feb 2010. File
      Not available unless: Your ID number contains 02
    • Nguku et al. An Investigation of a Major Outbreak of Rift Valley Fever in Kenya: 2006–2007. Am. J. Trop. Med. Hyg., 83(Suppl 2), 2010, pp. 5–13 File
      Not available unless: Your ID number contains 02
    • Bourtzis et al. Harnessing mosquito–Wolbachia symbiosis for vector and disease control. Acta Tropica. 2014. File
      Not available unless: Your ID number contains 02

    • Articles for the student seminar: STUDENT TO CHOOSE ONE OF THE TWO QUESTIONS TO ADDRESS

      Question 1: Are novel approaches to vector control going to stop arboviral outbreaks?

       

    • Frentiu FD, Zakir T, Walker T, Popovici J, Pyke AT, et al. (2014) Limited Dengue Virus Replication in Field-Collected Aedes aegypti Mosquitoes Infected with Wolbachia. PLoS Negl Trop Dis 8(2): e2688. doi:10.1371/journal.pntd.0002688 File
      Not available unless: Your ID number contains 02
    • van den Hurk AF, Hall-Mendelin S, Pyke AT, Frentiu FD, McElroy K, et al. (2012) Impact of Wolbachia on Infection with Chikungunya and Yellow Fever Viruses in the Mosquito Vector Aedes aegypti. PLoS Negl Trop Dis 6(11): e1892. doi:10.1371/journal.pntd.0001 File
      Not available unless: Your ID number contains 02
    • Dodson BL, Hughes GL, Paul O, Matacchiero AC, Kramer LD, et al. (2014) Wolbachia Enhances West Nile Virus (WNV) Infection in the Mosquito Culex tarsalis. PLoS Negl Trop Dis 8(7): e2965. doi:10.1371/journal.pntd.0002965 File
      Not available unless: Your ID number contains 02
    • Black Alphey and James. Why RIDL is not SIT. Trends in Parasitology. August 2011. File
      Not available unless: Your ID number contains 02
    • Bonus (optional): Carvahlo et at. Mass Production of Genetically Modified Aedes aegypti for Field Releases in Brazil. JOVE. January 2014 File
      Not available unless: Your ID number contains 02

    • Question 2: How can a One Health approach prevent future RVFV outbreaks?

    • Anyangu et al. Risk Factors for Severe Rift Valley Fever Infection in Kenya, 2007. Am. J. Trop. Med. Hyg., 83(Suppl 2), 2010, pp. 14–21 File
      Not available unless: Your ID number contains 02
    • Munyua et al. Rift Valley Fever Outbreak in Livestock in Kenya, 2006–2007 . Am. J. Trop. Med. Hyg., 83(Suppl 2), 2010, pp. 58–64 File
      Not available unless: Your ID number contains 02
    • Bird and Nichol. Breaking the chain. Rift Valley fever virus control via livestock vaccination. Current Opinion in Virology 2012, 2:315–323 File
      Not available unless: Your ID number contains 02
    • Anyamba et al. Prediction, Assessment of the Rift Valley Fever Activity in East and Southern Africa 2006–2008 and Possible Vector Control Strategies. Am. J. Trop. Med. Hyg., 83(Suppl2), 2010, pp. 43–51 File
      Not available unless: Your ID number contains 02
    • Bonus (optional): Olive, Goodman, and Reynes. The role of wild mammals in the maintenance of Rift Valley fever virus. J of Wildlife Diseases. 2012. File
      Not available unless: Your ID number contains 02

  • Monday, February 15, 2016; No Class - President's Day

  • Monday, February 22, 2016; 1:00 PM - 3:00 PM

    Lecture: Malaria

    Faculty:  Roly Gosling, Jimee Hwang

    Location:      Mission Hall 1109

    • Session Slides:

    • Required Reading:

      Gill G, Beeching N. Lecture Notes on Tropical Medicine 7th ed. Chapter on Malaria.

    • Tusting LS, Bousema T, Smith DL, Drakeley C. Measuring changes in Plasmodium falciparum transmission: precision, accuracy and costs of metrics. Adv Parasitol. 2014;84:151-208 (Table 3.1 only) File
      Not available unless: Your ID number contains 02
    • Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, Hemelaar S, Brown JM, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling RD. Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infectio File
      Not available unless: Your ID number contains 02
    • Hawley WA, Phillips-Howard PA, ter Kuile FO, Terlouw DJ, Vulule JM, Ombok M, Nahlen BL, Gimnig JE, Kariuki SK, Kolczak MS, Hightower AW. Community-wide effects of permethrin-treated bed nets on child mortality and malaria morbidity in western Kenya. Am J File
      Not available unless: Your ID number contains 02
    • Ch 9 Malaria, Bell Lalloo Tropical Medicine Lecture Notes 7th ed File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Bayoh MN, Walker ED, Kosgei J, Ombok M, Olang GB, Githeko AK, Killeen GF, Otieno P, Desai M, Lobo NF, Vulule JM, Hamel MJ, Kariuki S, Gimnig JE. Persistently high estimates of late night, indoor exposure to malaria vectors despite high coverage of insecti File
      Not available unless: Your ID number contains 02
    • Barry AE, Schultz L, Senn N, Nale J, Kiniboro B, Siba PM, Mueller I, Reeder JC. High levels of genetic diversity of Plasmodium falciparum populations in Papua New Guinea despite variable infection prevalence. Am J Trop Med Hyg. 2013 Apr;88(4):718-25. File
      Not available unless: Your ID number contains 02
    • Adam Bennett, Josh Yukich, John M Miller, Joseph Keatin, Hawela Moonga, Busiku Hamainza, Mulakwo Kamuliwo, Penelope Vounatsou, Richard W Steketee, Thomas P Eisele. The effect of climate and vector control coverage on malaria parasite prevalence in Zambia File
      Not available unless: Your ID number contains 02

  • Monday, February 29, 2016; 1:00 PM - 3:00 PM

    Lecture: Schistosomiasis

    Faculty:  Hugh Sturrock

    Location:  Mission Hall 1109

    • Required Reading:

    • Gryseels B, Polman K, Clerinx J, Kestens L: Human schistosomiasis. Lancet 2006, 368:1106-1118. File
      Not available unless: Your ID number contains 02
    • Brooker S: Spatial epidemiology of human schistosomiasis in Africa: risk models, transmission dynamics and control. Trans R Soc Trop Med Hyg 2007, 101:1-8. File
      Not available unless: Your ID number contains 02
    • Gray DJ, McManus DP, Li Y, Williams GM, Bergquist R, Ross AG: Schistosomiasis elimination: lessons from the past guide the future. The Lancet Infectious Diseases 2010, 10:733-736. File
      Not available unless: Your ID number contains 02
    • Rollinson D, Knopp S, Levitz S, Stothard JR, Tchuem Tchuenté L-A, Garba A, Mohammed KA, Schur N, Person B, Colley DG, Utzinger J: Time to set the agenda for schistosomiasis elimination. Acta Trop 2013, 128:423-440. File
      Not available unless: Your ID number contains 02
    • Lengeler C, Utzinger J, & Tanner M. Questionnaires for rapid screening of schistosomiasis in sub-Saharan Africa. Bull World Health Organ 2002, 80:3 File
      Not available unless: Your ID number contains 02
    • Brooker S, Kabatereine NB, Gyapong JO, Stothard JR, Utzinger J: Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa. Parasitology 2009, 136:1707-1718. File
      Not available unless: Your ID number contains 02
    • Clements AC, Lwambo NJ, Blair L, Nyandindi U, Kaatano G, Kinung'hi S, Webster JP, Fenwick A, Brooker S: Bayesian spatial analysis and disease mapping: tools to enhance planning and implementation of a schistosomiasis control programme in Tanzania. Trop Me File
      Not available unless: Your ID number contains 02

  • Monday, March 7, 2016; 1:00 PM - 3:00 PM

    Lecture: NTDs addressed by mass drug administration

    For the last 2 classes, the plan is for students to take over these sessions in small groups to address elimination and eradication programs, especially those targeting NTDs not already discussed. Sign-up for specific topics will occur several weeks into the quarter.

    Faculty:  Caryn Bern, various lecturers

    Location:      Mission Hall 1109

    • Session Slides:

    • Heymann DL. Disease Eradication and Control. In: Guerrant RL, Walker DH, Weller PF, eds. Tropical infectious diseases: principles, pathogens and practice. Edinburgh, Scotland: Churchill Livingstone Elsevier; 2011:40-44. File
      Not available unless: Your ID number contains 02
    • Hopkins DR. Disease Eradication. N Engl J Med 2013;368:54-63. File
      Not available unless: Your ID number contains 02

  • Monday, March 14, 2016; 1:00 PM - 3:00 PM

    Lecture: Eradication and elimination programs

     

    Faculty:  Caryn Bern, various instructors

    Location:      Mission Hall 1109

    • Session Slides: