Section outline

  • Lecture: Overview of epidemiology of aging & course introduction

    Q: What is the epidemiology of aging?

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • Crimmins EM. Trends in health of the elderly. Ann Rev Public Health 2004. File
      Not available unless: Your ID number contains 02
    • Lutz W, Sanderson W, Scherbov S. The coming acceleration of global population aging. Nature 2008;451:716-719. File
      Not available unless: Your ID number contains 02
    • Fried LP et al. Frailty in older adults: Evidence for a phenotype J of Geron: Medi Sciences 2001. Vol 56a. File
      Not available unless: Your ID number contains 02
  • Lecture: Biology of aging

    Basics of biological/physiological changes common in aging populations.

    Q: What are three social, biological or genetic factors that influence longevity?

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • crewes 2003 File
      Not available unless: Your ID number contains 02
    • TELOMERS IN DETROIT 2015 File
      Not available unless: Your ID number contains 02
  • Lecture: Aging-related diseases & disorders

    Changes in prevalence and incidence of various diseases with age. Frailty as an aging syndrome

    Q: What is frailty and how will it affect treatment of patients?

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • Ferrucci L, Giallauria F, Guralnick J. Epidemiology of aging. Radiol Clin North Am 2008;46:643-645 File
      Not available unless: Your ID number contains 02
    • Finn M, et al Influence of frailty on outcomes in CVD..Rev Esp Cardio 2015; 68(8): 653 File
      Not available unless: Your ID number contains 02
    • Frisoli A, et al Frailty predictors…Arch Geron Ger 2015 File
      Not available unless: Your ID number contains 02
  • Lecture: Epidemiologic methods in aging

    Risk factors for disease in the elderly; competing risk/role of selective survival; age/period/cohort effects; measurement difficulties (e.g., due to physical, cognitive or sensory impairments)

    Q: What is the likely effect on risk estimates for CVD in people over 80 of a major flu epidemic that occurred when they were 30?

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • Newman AB. Overview of design, implementation and analyses of longitudinal studies on aging. 2010 File
      Not available unless: Your ID number contains 02
    • Goodwin JS. Embracing complexity 2003. File
      Not available unless: Your ID number contains 02
    • Rajan K. Cognitive turning point. J of Gerontology: Med Scie (2017: Vol 00.) File
      Not available unless: Your ID number contains 02
    • Raghanuthan TE. Missing data. ARPH 2004. File
      Not available unless: Your ID number contains 02
  • Lecture: Methods of analysis: Application of longitudinal methods in aging populations

    Longitudinal analysis and aging populations.

    Q: What statistical models are most appropriate for modeling the association between age and change over time in cognitive test scores:

    Faculty:  Dr. Steve Cummings, Professor Emeritus, Department of Medicine (General Internal Medicine), UCSF

    Location:  Mission Hall 1105

    • Session Slides:

    • Required Reading:

    • Doll R. mortality in relation to smoking: 50 years’ observations on male British doctors. BMJ 2004. File
      Not available unless: Your ID number contains 02
    • Doll R, mortality of doctors in relation to their smoking habits; BMJ 2004 File
      Not available unless: Your ID number contains 02
    • Mishra G et al Structured approach Int J Epid 2009 File
      Not available unless: Your ID number contains 02
  • Lecture: Guidelines for statin use in elderly

    Presentation of key recommendations for treatment in people aged 60+

    Q: Should people over 65 be treated differently with statins? What are the pros and cons?

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • Odden MC, Cost effectiveness and population impact of statins. Annals of Int Medicine 2015. File
      Not available unless: Your ID number contains 02
    • Alperovitch Primary prevention with lipid lowering…BMJ 2015: 350 File
      Not available unless: Your ID number contains 02
    • Hirabayashi N. Assoc diabetes and hippocampal atrophy . Diabetes Care; 2016:39:1543-1549. File
      Not available unless: Your ID number contains 02
  • Lecture: Hypertension control in the elderly

    Comparison of JNCI 8 guidelines to recommendations of SPRINT trial

    Q: What is the evidentiary base for the JNCI 8 recommendations in people over 65?

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • SPRINT TRIAL NEJM 2015 File
      Not available unless: Your ID number contains 02
    • JNCI 8 guidelines on BP control 2014. File
      Not available unless: Your ID number contains 02
  • Lecture: Cognitive function and dementia

    Changes in cognition with age; risk factors for cognitive impairment and dementia; potential for prevention.

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • Barnes et al. AD projections Lancet 2011 File
      Not available unless: Your ID number contains 02
  • Lecture: Depression/mood

    Changes in prevalence of mood disorders with age; risk factors and outcomes

    Faculty:  Dr. Christine Ritchie, Palliative Care in Aging, Harris Fishbon Distinguished Professor in Clinical Translational Research and Aging, UCSF.

    Location:  Mission Hall 1105

    • Session Slides:

    • Required Reading:

    • Byers, 2010 File
      Not available unless: Your ID number contains 02
  • Lecture: Physical function, disability and comorbidity

    Factors influencing physical function, disability and comorbidity in older populations; risk factors and outcomes.

    Faculty: Mary Haan

    Location: Mission Hall 1105

     

    • Session Slides:

    • Required Reading:

    • Covinsky, 2009 File
      Not available unless: Your ID number contains 02
    • Calderon-Larranaga A. Assessing and measuring Multimorbidity..(J Gerontoloogy: Med Scie 12/21/16 File
      Not available unless: Your ID number contains 02
    • Garcia MA et al. Physical functioning and disability trajectories by age of migration among Mexican Elders in the US. J of Gerontology: Social Sciences; 2017, Vol no 00 No, 00 1-11 File
      Not available unless: Your ID number contains 02
  • Lecture:

    TBA

    Faculty:  Mary Haan

    Location:  Mission Hall 1105