Hi Ricky,
You have chosen a subject near and dear to my heart: fluid resuscitation in sepsis! I am not as familiar with the adult ICU literature and guidelines; what are the current international guidelines for sepsis and resuscitation in adults? Is it EGDT, which includes early, large volume fluid resuscitation? Or, has someone or a group, like the WHO, suggested a different approach to resuscitation in resource-constrained regions (I know that they have for children)? Also, what do you make of the PRoMISe, ARISE and ProCESS results from HICs that do not show a benefit of EGDT?
Fluid resuscitation is a big, controversial, and very interesting question. Do you know which implementation gap you are interested in and want to address?
Teresa