This course assumes a basic understanding of magnetic resonance physics and will cover in detail the topic of nuclear magnetic resonance spectroscopy including both in vitro and in vivo applications. The course will cover basic theory, underlying biochemistry and physiology, basic and advanced techniques for acquiring and processing MR spectroscopic data, and biomedical applications for this emerging medical imaging modality. The course will also have four hands-on labs that will allow students to actually acquire and analyze spectroscopy data from human tissue extracts, a 3D cell culture bioreactor and a murine model of cancer. In addition to 2 didactic lectures per week, the course will have weekly discussion sessions focused on understanding the material covered in both lectures and labs. While not a pre-requisite, taking either Bioengineering 240, Biomedical Imaging 201, or a similar course that covers the basics of magnetic resonance imaging or NMR is advised.
- Instructor: John Kurhanewicz