Epidemiologic Methods II is designed to extend upon the topics taught in Epidemiologic Methods (EPI 203) and to include further instruction in the methodology specific to epidemiologic research. Topics will include: the interrelationships between various measures of disease occurrence and association; concepts of attributable risk; interactions; practical and theoretical considerations of the most common study designs in observational research; methods of reducing confounding including matching, instrumental variables and propensity scores. More advanced analytic techniques specific to epidemiologic research are covered, including regression model building and diagnostics and hierarchical modeling. There is also in depth instruction in quantitative bias analysis for misclassification, selection bias, and unmeasured confounding.

The main objective of the course is to enhance a student’s ability to design and conduct unbiased and efficient research. The goals are to:

  • Introduce students to advanced-level epidemiologic methods;
  • Synthesize understanding in selected topics of advanced epidemiological methods; and
  • Create a forum for discussion of methodological and theoretical issues of epidemiologic methodology and to put them into the perspective of the current knowledge of these issues.