Section outline

  • Quantitative Bias Analysis (QBA) 

    The focus of this workshop is methods for conducting quantitative bias analysis in epidemiologic research. We will first provide a brief introduction to confounding, information bias, and selection bias using causal diagrams. Next, we will discuss deterministic and probabilistic bias analysis. Dr. Mayeda will discuss examples of specific biases in her own work on determinants of cognitive decline in older adults. At the end of the workshop, participants should walk away with an understanding of the motivations behind quantitative bias analysis and how to use tools for conducting quantitative bias analysis.

    The first two hours will contain the material for which students in EPI207 are responsible; the last hour is optional for the class.

    Faculty:  Elizabeth Rose Mayeda

    • Files to Download BEFORE Part 2 QBA
      Uploaded 10/20/21, 23:41


    • Required Reading:


    • Orsini N, et al. A tool for deterministic and probabilistic sensitivity analysis of epidemiologic studies. Stata Journal. 2008;8(1):29-48. File
      Not available unless: You belong to Registered Students Only

    • Optional Reading:


    • Mayeda ER, et al. A simulation platform for quantifying survival bias: an application to research on determinants of cognitive decline. American Journal of Epidemiology. 2016 Sep 1;184(5):378-87. (copy) File
      Not available unless: You belong to Registered Students Only
    • Hernán MA, Hernández-Díaz S, Robins JM. A structural approach to selection bias. Epidemiology. 2004;15(5):615-625. File
      Not available unless: You belong to Registered Students Only
    • Fox MP, Lash TL, Greenland S. A method to automate probabilistic sensitivity analyses of misclassified binary variables. International journal of epidemiology. 2005;34(6):1370-1376. File
      Not available unless: You belong to Registered Students Only
    • Last TL, et al. Good practices for quantitative bias analysis. International Journal of Epidemiology. 2014;43(6):1969-1985. File
      Not available unless: You belong to Registered Students Only

    • Session Slides:

    • QBA Part I File
      Uploaded 03/4/22, 12:53
    • QBA Part II File
      Uploaded 03/4/22, 12:54

    • Session Audio/Video Recording (Access restricted to registered students):

    • Class Recording - Week 9 Media Resource
      Not available unless: You belong to Registered Students Only

    • Assignment:

      Due Thursday, March 10, 2022 at the beginning of lecture

    • QBA Homework Questions File
      Uploaded 03/4/22, 12:58
    • Homework #7 Submission Assignment

    • Assignment Answer Key (access restricted to registered students):

    • QBA Homework Answer Key File
      Not available unless: You belong to Registered Students Only