Section outline

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  • Thursday, April 2, 2015; 1:00 PM - 2:30 PM

    Lecture: Designing a systematic review
    Indications and overview of the steps of systematic reviews, how to formulate research questions and developing a protocol, Data sources, search strategy and publication bias; inclusion and exclusion criteria, quality assessment, data abstraction forms, selection of studies, homogeneity.

    Faculty:  Dejana Braithwaite

    Location:      Mission Hall 1400

    • Prospectus:

    • Course Overview Page.2015 File

    • Session Slides:

    • Lecture 1.2015 File
    • SR lecture April 2 2015 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Bent - AJIC - Systematic Reviews File
      Not available unless: Your ID number contains 02

    • Optional Reading:

      Systematic Reviews in Health Care, chapters 2,3,4 & 5

    • Moher D, Liberati A , Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. File
      Not available unless: Your ID number contains 02
    • Jadad AR et al. Assessing the Quality of Reports of Randomized Controlled Clinical Trials: Is Blinding Necessary? Controlled Clinical Trials. 1996;17:1-12. File
      Not available unless: Your ID number contains 02
    • Hayden JA et al. Evaluation of the quality of prognostic studies in systematic reviews. Annals of Internal Medicine. 2006;144:427-437. File
      Not available unless: Your ID number contains 02

  • Thursday, April 9, 2015; 1:00 PM - 2:30 PM

    Small Group Sessions: Section I

    Part A: 60 min: Developing a Protocol for Systematic Review
    Part B: 30 min: Literature Search with Min-Ling Fan

    Faculty: Elaine Allen, Dejana Braithwaite, Ashok Krishnaswami (Part A)\Min-Ling Fan (Part B)

    Location:  MH 1106 (Allen), MH 2105 (Braithwaite), MH 2106 (Krishnaswami)/MH 1400 (Fan)

    • Session Slides:

    • Literature Searching for SR-4-2015 File

    • Required Reading:

    • Articles A, B, C, D File
      Not available unless: Your ID number contains 02

    • Assignment:

    • Section 1.2015 File

  • Thursday, April 16, 2015; 1:00 PM - 2:30 PM

    Lecture: Analytical Methods
    Fixed and random effects models, summary estimates of effect and variance, subgroup and sensitivity analysis, statistical approaches to publication bias, presenting results of meta-analysis.

    Faculty:  Dejana Braithwaite, I. Elaine Allen

    Location:  Mission Hall 1400

    • Session Slides:

    • Lecture 2 2015 File
    • Analytics Meta-4-16new File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Optional Reading:

      Egger M, Davey Smith G, Altman D. Systematic reviews in health care: Meta-analysis in context. Chapters 15-17.

    • Egger M, Ebrahim S, Smith GD. Where now for meta-analysis? International Journal of Epidemiology. 2002;31:1-5. File
      Not available unless: Your ID number contains 02
    • Shrier I, Platt RW, Steele RJ. Mega-trials vs. meta-analysis: Precision vs. heterogeneity? Contemporary Clinical Trials. 2007;28:324–328 File
      Not available unless: Your ID number contains 02
    • Shapiro S. Point/Counterpoint: Meta-analysis of observational studies: meta-analysis/shmeta-analysis. American Journal of Epidemiology. 1994;140:771-778. File
      Not available unless: Your ID number contains 02
    • Alder et al. Meta-analysis of mortality and cancer incidence among workers in the synthetic rubber-producing industry. American Journal of Epidemiology. 2006;164:405-420. File
      Not available unless: Your ID number contains 02
    • Moher D, Schulz KF, Altman DG. The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials. Annals of Internal Medicine. 2001;134:657-62. File
      Not available unless: Your ID number contains 02

  • Thursday, April 23, 2015; 1:00 PM - 2:30 PM

    Section: Performing a Meta-analysis

    Faculty:  I Elaine Allen, Dejana Braithwaite, Ashok Krishnaswami

    Location: Mission Hall 1400

    • Session Slides:

    • Assignment:

    • Section 2 2015 File

    • Datasets:

    • hw02-2 File
    • hw02-1 File

  • Thursday, April 30, 2015; 1:00 PM - 2:30 PM

    Lecture: Advanced techniques in meta-analysis

    Faculty: I. Elaine Allen

    Location:      Mission Hall 1400

    • Session Slides:

    • Lecture 3 2015 File
    • AdvancedTechniques4-30 File
    • WWTBM - EBM File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • METANDI stata File
      Not available unless: Your ID number contains 02
    • Stata meta.analysis File
      Not available unless: Your ID number contains 02
    • Evid Based Mental Health-2014-Chaimani-111-6 File
      Not available unless: Your ID number contains 02

    • Optional Reading:

      Egger M, Davey Smith G, Altman D. Systematic reviews in health care: Meta-analysis in context. Chapters 15-16

      Leeflang MMG, Deeks JJ, Gatsonis C, Bossuyt PMM. Systematic reviews of diagnostic test accuracy. Ann Int Med. 2008;149:889-897.

    • Resources:

    • Appendix S1-StataCommands File

  • Thursday, May 7, 2015; 1:00 PM - 2:30 PM

    Journal Club

    Faculty:  Elaine Allen, Dejana Braithwaite, Ashok Krishnaswami

    Location: MH 1400

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Alter HJ et al. Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-anlaysis. Annals of Emergency Medicine. 2000;36:191-197. File
      Not available unless: Your ID number contains 02
    • Rowe BH et al. Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Annals of Emergency Medicine. 2000;36:181-190. File
      Not available unless: Your ID number contains 02

    • Assignment:

    • Section 3 2015 File

    • Final Exam: 

    • Final Exam Due Date: Complete and e-mail by May 14, 5pm, to: systematicreviews2015@gmail.com

    • SR EXAM 2015 File

  • Topic 10