Section outline


    • Systematic Reviews

      EPI 214 Spring 2017 (1 unit).
      Course Director: Steve Bent, MD.
      Professor, Department of Medicine
      Dejana Braithwaite, PhD, MS
      Associate Professor, Department of Epidemiology and Biostatistics
      I. Elaine Allen, PhD
      Course Biostatistical Director: 

  • Lecture 1: Designing a Systematic Review
    Indications and overview of the steps of systematic reviews, how to formulate research questions and developing a protocol, Data sources, search strategy and publication bias; inclusion and exclusion criteria, quality assessment, data abstraction forms, selection of studies, homogeneity.

    Faculty:  Dejana Braithwaite
     
    Location:  Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Bent - AJIC - Systematic Reviews File
      Not available unless: Your ID number contains 02
    • Grant et al-2009-Health Information Libraries Journal File
      Not available unless: Your ID number contains 02
    • Optional Reading:

      Systematic Reviews in Health Care, chapters 2,3,4 & 5

    • Moher D, Liberati A , Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. File
      Not available unless: Your ID number contains 02
    • Cooke A, Smith D, Booth A. Beyond PICO: the SPIDER tool for qualitative evidence synthesis. Qual Health Res. 2012 Oct;22(10):1435-43 File
      Not available unless: Your ID number contains 02
    • Ioannidis JP. The Mass Production of Redundant, Misleading, and Conflicted Systematic Reviews and Meta-analyses. Milbank Q. 2016 Sep;94(3):485-514. doi: 10.1111/1468-0009.12210. File
      Not available unless: Your ID number contains 02
  • Lecture 2: Designing a Systematic Review

    Faculty: Dejana Braithwaite

    Location:  MH 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Optional Reading:

    • Li 2015 - Innovations in SR Prep File
      Not available unless: Your ID number contains 02
  • Lecture 3: Systematic Review and Meta-analysis: Analytical Methods

    Faculty:  Steve Bent

    Location:  
    Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Optional Reading:

    • Moher D, Schulz KF, Altman DG. The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials. Annals of Internal Medicine. 2001;134:657-62. File
      Not available unless: Your ID number contains 02
    • Juni et al. Hazards of scoring the quality of clinical trials for meta-analysis. JAMA. 1999;1054-60. File
      Not available unless: Your ID number contains 02
    • Berlin JA, Golub RM. Meta-analysis as evidence: building a better pyramid. JAMA. 2014;312:603-5. File
      Not available unless: Your ID number contains 02
    • Dechartres A, Altman DG, Trinquart L, Boutron I, Ravaud P. Association between analytic strategy and estimates of treatment outcomes in meta-analyses. JAMA. 2014;312:623-30. File
      Not available unless: Your ID number contains 02
  • Lecture 4: Problem Set: Performing a Meta-analysis

    Faculty:  Steve Bent

    Location: Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Datasets:

  • Lecture 5: New and Advanced Methods for Pooling Studies 

    Faculty: I. Elaine Allen

    Location:  
    Mission Hall 1400

  • Lecture 6: Performing a Critique of a Systematic Review: Journal Club

    Faculty:  Ashok Krishnaswami

    Location: MH 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Alter HJ et al. Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-anlaysis. Annals of Emergency Medicine. 2000;36:191-197. File
      Not available unless: Your ID number contains 02
    • Rowe BH et al. Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Annals of Emergency Medicine. 2000;36:181-190. File
      Not available unless: Your ID number contains 02
    • Take Home Final Exam: 

    • Final Exam Due: May 18th (by e-mail to ucsfsystematicreviews2017@gmail.com)