question 9

question 9

by Laura Koth -
Number of replies: 5

I don't understand how to get the pre-test prob from the question stem.

do you assume that the proportion of positive tests is the same as the pre-test probability?

thank you

In reply to Laura Koth

Re: question 9

by Thomas Newman -

Figuring out the pre-test probability is part of this problem and I don't want to give it away, but no,, I would not assume that the proportion of positive tests is the same as the pre-test probability.

Here's a hint that might clarify the difference.  In the 2 x 2 tables we've been making the pretest probability is the left column total over the total N and the proportion of positive tests would be the 1st row total over the total N.





In reply to Thomas Newman

Re: question 9

by Laura Koth -

thanks. on this point, I hope you read my class feedback comments which i have included in my final exam

In reply to Thomas Newman

Re: question 9

by Nicholas Arger -

Sorry, now I am confused - does D+ refer to those who actually had the disease (and were thus referable) or those who tested positive? Just want to make sure I am clear on the language here since D+ is called "referable" and what is being needed is pre-test probability of disease.

In reply to Nicholas Arger

Re: question 9

by Thomas Newman -

OK, I think I understand the confusion better now.  The "Disease" here is "referable diabetic retinopathy."  The "test" is the certainty score produced by the machine learning algorithm.   Does that help?

Tom

In reply to Thomas Newman

Re: question 9

by Nicholas Arger -

Got it - so when you says, of 8788 evaluable images, 683 were D+ , D+ refers to those with disease = those who had referable diabetic retinopathy. If that is the case, the problem is clear now.

Thanks,

Nikko