Learning Objectives

Objectives:

Provide an introduction to analytical issues that are particularly relevant to healthcare intervention studies, including interrupted time series analysis, cluster randomized trials, and hierarchical models

List the situations in which a cluster randomized trial is the most feasible

List the disadvantages of to a cluster randomized trial

List the situations in which an interrupted time series is the most feasible

List the disadvantages to an interrupted time series design

Describe what types of statistical analyses are necessary for cluster randomized trials and interrupted time series

Describe and define the design effect

Use the design effect or estimates of between and within cluster variability to do sample size calculations for cluster randomized trials

Learning Activities: