Section outline

  • Target Trials


    Strengths and limitations of randomized clinical trials; similarities and differences between components of randomized clinical trials and observational studies; application of using a “target trial” to make causal inferences from cohort studies.

    Faculty:  June Chan

    • Required Reading (please read PRIOR to watching the lectures):

      Rothman, Greenland and Lash 2008 (RGL), Modern Epidemiology, Ch. 6 (focus on RCT and COH) & skim Chapter 7. Please note, RGL Chapter 7 will also be assigned for a future lecture on Person Time/Bias in Cohorts.


    • Recorded Lectures (please watch PRIOR to class):

      Access restricted to registered students

    • Target Trials - Part 1 Media Resource

    • There is no recording associated with the Target Trials - Part 2 slides. Please just review the slides.

    • Target Trials - Part 3 Media Resource

    • Session Slides:

    • Target Trials - Part 1 File
    • Target Trials - Part 2 File
    • Target Trials - Part 3 File
    • Target Trials - Part 4 (In-Class) & Appendix File
    • UPDATED In-Class Exercise slides File
      Uploaded 01/28/21, 13:39
    • In-Class Exercise Target Trials Sample Answers v3 File
    • Target Trials - All Parts File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Class Recording - Week 4 Media Resource
      Not available unless: You belong to a group in Registered Students Only

    • Assignment:

      Due Thursday, February 4, 2021 at the beginning of lecture

    • Article to Read for HW - Lawson, et al. J Natl Cancer Inst 2007 File
      Not available unless: You belong to a group in Registered Students Only
    • EPID 207 W21 Target Trials HW Questions File
      Not available unless: You belong to Registered Students Only
      Uploaded 01/28/21, 13:42
    • Homework #3 Submission Assignment

    • Watch pre-recorded lecture on Matching in Observational Studies

    • Assignment Answer Key (access restricted to registered students):

    • Baseline AARP Diet Questionnaire (Supplemental FYI Only) File
    • 210203 EPI207 RCT Coh Target Trials KEY ONLY to POST File
      Not available unless: You belong to Registered Students Only
      Uploaded 02/3/21, 11:07