odds ration from slide no. 12

odds ration from slide no. 12

by Foram Choksi -
Number of replies: 2

Hi Dr. Iona, 

Could you please explain how we got those odds ratios on slide no. 12. I am not very clear on that one. 

Thanks

Best,

Foram

The table

In reply to Foram Choksi

Re: odds ration from slide no. 12

by Thomas Hoffmann -

Hi Foram

This e-mail will be best viewed copied and pasted into a fixed width font.

Page 12 is the one with

Strata  Cases  Controls  Odds Ratio
G+E+    25     2         34.7
G+E-    10     4         6.9
G-E+    84     63        3.7
G-E-    36     100       Reference

So the first Odds Ratio (34.7) is calculated from the 2x2 table

Strata  Cases  Controls  Odds Ratio
G+E+    25     2         34.7
G-E-    36     100       Reference

which you would calculate, depending on how you learned this

OR = (25 x 100) / (36 x 2) = 34.7
OR = (25 / 2) / (36 / 100) = 34.7  [Ratio of odds]

You can then solve similarly for the other 2x2 tables. The key is that each line is with respect to the reference. so the other two are first

Strata  Cases  Controls  Odds Ratio
G+E-    10     4         6.9
G-E-    36     100       Reference

OR = (10 x 100) / (4 x 36) = 6.9

Strata  Cases  Controls  Odds Ratio
G-E+    84     63        3.7
G-E-    36     100       Reference

OR = (84 x 100) / (63 x 36) = 3.7

Best,
Tom

In reply to Thomas Hoffmann

Re: odds ration from slide no. 12

by Foram Choksi -

Thanks for the explanation Dr. Tom


Best,

Foram