Section outline

  • Live Lecture: Quantitative Bias Analysis (QBA) 

    The focus of this workshop is methods for conducting quantitative bias analysis in epidemiologic research. We will first provide a brief introduction to confounding, information bias, and selection bias using causal diagrams. Next, we will discuss deterministic and probabilistic bias analysis. Dr. Mayeda will discuss examples of specific biases in her own work on determinants of cognitive decline in older adults. At the end of the workshop, participants should walk away with an understanding of the motivations behind quantitative bias analysis and how to use tools for conducting quantitative bias analysis.

    Please RSVP to event: https://bit.ly/2FrT8rt

    Faculty:  Elizabeth Rose Mayeda

    Location:  Mission Hall 1401


    • Session Slides:

    • QBA session slides Dr. Mayeda File
    • QBA session Slides Dr. Mayeda Part 2. File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      Orsini, N., Bellocco, R., Bottai, M., Wolk, A. and Greenland, S., 2008. A tool for deterministic and probabilistic sensitivity analysis of epidemiologic studies. Stata Journal, 8(1), pp.29-48.



    • Orsini article for QBA HW File
      Not available unless: Your ID number contains 02

    • Optional Reading:


    • Hernán MA, Hernández-Díaz S, Robins JM. A structural approach to selection bias. Epidemiology. 2004;15(5):615-625. File
      Not available unless: Your ID number contains 02
    • Fox MP, Lash TL, Greenland S. A method to automate probabilistic sensitivity analyses of misclassified binary variables. International journal of epidemiology. 2005;34(6):1370-1376. File
      Not available unless: Your ID number contains 02
    • Last TL, et al. Good practices for quantitative bias analysis. International Journal of Epidemiology. 2014;43(6):1969-1985. File
      Not available unless: Your ID number contains 02
    • Mayeda ER, et al. A simulation platform for quantifying survival bias: an application to research on determinants of cognitive decline. American Journal of Epidemiology. 2016 Sep 1;184(5):378-87. File
      Not available unless: Your ID number contains 02
    • Mayeda ER, et al. Does selective survival prior to study enrolment attenuate estimated effects of education on rate of cognitive decline in older adults? A simulation approach for quantifying survival bias in life course epidemiology. File
      Not available unless: Your ID number contains 02
    • Mayeda ER, et al. Can survival bias explain the age attenuation of racial inequalities in stroke incidence? A simulation study. Epidemiology. 2018 Jul;29(4):525-532. File
      Not available unless: Your ID number contains 02

    • Assignment:

    • QBA HW v5 QUESTIONS ONLY 2019 final File

    • Assignment Due Date: February 28, 2019 at the beginning of Small Group Section

    • Week #5 Homework Submission Assignment

    • Assignment Answer Key (access restricted to registered students):