Section outline

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  • Monday, August 1, 2016, 9:00 AM - 10:15 AM

    Lecture: The Research Question

    Introduction to the course; components ("anatomy") of a research protocol and "physiology" of research; examples from Dr. Newman's neonatal jaundice research.

    Faculty:  Tom Newman

    Location:      HSW 302

  • Monday, August 1, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen CL-211/CL212, Hsu CL-213/214, Smoot CL-215/216, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

    • Assignment:

      Download and review full assignment below. Most important:

        1. Read Chapters 1 & 2 of DCR-4
        2. Choose a research question.
        3. Identify and meet with your mentor
        4. Bring a hard copy of a 1-sentence version of your Research Question and a 1/2 to 3/4 page Significance section to class.
        5. Use a citation management program for the references. Take a class if needed.

    • ASSIGNMENT ONE 2016.dueWeekOne.080116 File

    • Assignment Due Date:

      Assignment 1, to be completed before August 1

      Assignment 2, due August 4 at Noon

  • Wednesday, August 3, 2016, 9:00 AM - 10:15 AM

    Lecture: Subjects and variables

    Target and accessibile populations; inclusion and exclusion criteria; balancing feasibility and generalizability; sampling; types of variables and measurements; and maximizing precision and accuracy.

    Faculty:  Doug Bauer

    Location:      HSW 302

    • Session Slides:

    • Bauer subjects measurements 8.16 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      DCR-4 Chapter 3: Choosing the Study Subjects

      DCR-4 Chapter 4: Planning the Measurements

    • How do we know what we know? This is a 52 minute recorded lecture by Tom Newman URL
      Not available unless: Your ID number contains 02

    • Optional Reading:

  • Wednesday, August 3, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen S-168, Hsu S-157, Smoot S-172, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

    • Assignment:

      Download and review full assignment below. Most important:

        1. Read chapters 3 and 4 of DCR-4.
        2. Compose an outline of your study.
        3. Include a more detailed "Study Subjects" and “Variables” section.
        4. Make an appointment to meet with your mentor.
        5. Watch TN's presentation "How do we know what we know?"

    • ASSIGNMENT TWO 2016.dueWeekOne.080416 File

    • Assignment Due Date:  Assignment 2 due August 4 at Noon

  • Friday, August 5, 2016; 12:00 PM - 1:00 PM

    Lecture:  Brown Bag

    What you always wanted to know about IRB/CHR but were afraid to ask.  What it means for students and Residents 

    Faculty:  Chris Ryan
     
    Location:  S-214 (Medical Science Building at Parnassus)

  • Monday, August 8, 2016; 9:00 AM - 10:15 AM

    Lecture: Study Designs

    Faculty:  Kirsten Bibbins-Domingo

    Location:      HSW 302

    • Session Slides:

    • KBD DCR Lecture Slides 08082016 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      DCR-4 Chapter 7: Designing Cross-Sectional and Cohort Studies

      DCR-4 Chapter 8: Designing Case-Control Studies

    • Optional Reading:

  • Monday, August 8, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Discussion of Assignment Three

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen S-168, Hsu S-157, Smoot S-172, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

    • Assignment:

              Download and review full assignment below. Most important:

        1. Read Chapters 7 and 8 of DCR-4 (and either 12,13 or 18 depending on your study).
        2. Have a clear, detailed understanding of exactly how at least one predictor and one outcome variable for your study will be (or was) measured
        3. Have experience providing tips to colleagues
        4. Be able to list and explain the advantages and disadvantages of basic observational study designs, including case-control, cross-sectional and cohort studies
        5. Understand simple statistics and the application to each of your studies

    • ASSIGNMENT THREE 2016.due WeekTwo.081116[1] File

    • Assignment Due Date: August 11th at NOON

  • Wednesday, August 10, 2016, 9:00 AM - 10:15 AM

    Lecture: Introduction to Statistics

    Biostatistic pearls.  How to interpret P values, Standard error versus Standard deviation.  Confidence intervals.  Adjustment in multivariable analyses.
     
    Faculty:  Charles McCulloch
     
    Location:      HSW 302

    • Session Slides:

    • DCR lecture biostat 2016 File
    • DCR lecture biostat 2016 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      DCR-4 Chapter 5: Underlying Statistical Principles (starting on page 46).

  • Wednesday, August 10, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Discussion of Assignment Three

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen S-168, Hsu S-157, Smoot S-172, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

      

    • Assignment:

      Download and review full assignment below.  Most important:

      1. Read chapters 5 (starting on page 46) in DCR-4.  You would have previously read chapters 7 and 8 of DCR-4 (and either 12, 13 or 18 depending on your study)
      2. Have a clear, detailed understanding of exactly how at least one predictor and one outcome variable for your study will be (or was) measured
      3. Have experience providing tips to colleagues
      4. Be able to list and explain the advantages and disadvantages of basic observational study designs, including case-control, cross-sectional and cohort studies
      5. Understand simple statistics and the application to each of your studies

    • Assignment Due Date:  Assignment 3 due for discussion in section today.  Due electronically August 11th at Noon to Section Leader

  • Friday, August 12, 2016, 12:00 PM - 1:00 PM

    Lecture:  Brown Bag

    Biostats for life

    Faculty: Chuck McCullough

    Location: S-214 (Medical Science Building at Parnassus)


  • Monday, August 15, 2016, 9:00 AM - 10:15 AM

    Lecture: Sample Size

    An introduction to the concepts and information needed to estimate sample sizes for various types of studies.  It includes suggestions for making more affordably sized studies

    Faculty: Steve Cummings

    Location:  HSW 302

    • Session Slides:

    • Sample Size 2016 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      DCR-4 Chapters 5 and 6

  • Monday, August 15, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

     

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen S-168, Hsu S-157, Smoot S-172, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

    • Assignment:

              Download and review full assignment below. Most important:

        1. Provide a contrasting point of view to the traditional view that studies with <80% power are not worthwhile
        2. Be very comfortable with the 1-sentence study plan summary
        3. Have justified the decisions/assumptions you used to estimate your sample size
        4. Know how to use a sample size calculator and the tables in the book to estimate sample size, given the decisions and assumptions you justified

    • ASSIGNMENT FOUR 2016.dueWeekThree.081816 File

  • Wednesday, August 17, 2016; 9:00 AM - 10:15 AM

    Lecture: Causality/Clinical Trials 

    Drawing causal inference; chance, bias, and confounding: pros and cons of observational studies and randomized controlled trials; examples from the diabetes literature

    Faculty:  Deborah Grady
     
    Location:  HSW 302

    • Session Slides:

    • Causal Inference 0816 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      DCR-4 Chapter 9: Enhancing Causal Inference in Observational Studies

      DCR-4 Chapter 10:  Designing a Randomized Blinded Trial

      DCR-4 Chapter 11: Alternative Trial Designs and Implementation Issues

  • Wednesday, August 17, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Discussion of Assignment Four

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen S-168, Hsu S-157, Smoot S-172, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

    • Assignment:

       Download and review full assignment below. Most important:

        1. Provide a contrasting point of view to the traditional view that studies with <80% power are not worthwhile
        2. Be very comfortable with the 1-sentence study plan summary
        3. Have justified the decisions/assumptions you used to estimate your sample size
        4. Know how to use a sample size calculator and the tables in the book to estimate sample size, given the decisions and assumptions you justified
        5. Be able to propose a logical (if not feasible) alternative design for your research question

    • ASSIGNMENT FOUR 2016.dueWeekThree.081816 File

    • Assignment Due Date:  Final Protocol Due 5pm, Monday, August 22, 2016.

  • Friday, August 19, 2016; 12:00 PM - 1:00 PM

    Lecture: Brown Bag

    Career Panel/Leadership for Students and Residents: How to connect the dots to the future 

    Location:   S-214 (Medical Science Building at Parnassus)

  • Monday August 22, 2016; 9:00 AM - 10:15 AM

    Lecture: Questionnaires and qualitative methods

    Development of questionnaires; adapting existing instruments or items vs creating new ones; pretesting to identify ambiguities.

    Faculty:  Miriam Kuppermann

    Location:      HSW 302

    • Session Slides:

    • Kuppermann DCR 082216 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      DCR-4 Chapter 15: Designing Questionnaires and Interviews

      DCR-4 Chapter 16: Data Management

    • Final Exam Due Date: Final Protocol Due 5pm, Monday, August 22, 2016.

  • Monday, August 22, 2016, 10:15 AM - 12:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Discussion of questionnaires.

    Faculty: Beth Cohen, Raymond Hsu, Betty Smoot, Daniel West, Hampson Lindsay, Vasantha Jotwani, Cassie Kline, Jonathan Lee, Mitchell Lunn, Kala Metha

    Location:  Cohen S-168, Hsu S-157, Smoot S-172, West S-159, Hampson S-180, Jotwani S-174, Kline S-176, Lee Online, Lunn S-178, Metha S-163

     

    • Assignment Due Date: 5:00 PM Monday August 22, 2016

       

  • Wednesday, August 24, 2016, 10:00 AM - 1:00 PM

    Final Peer Review Sessions

    Faculty: TBA

    Location: TBA