EPI 213: Decision and Cost Effectiveness Analysis in Medicine (Winter 2019)

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    Decision and Cost-Effectiveness Analysis in Medicine EPI 213 Winter 2019 (2 or 3 units). Course Director: Elliot Marseille, DrPh, MPP

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• Select section Thursday, January 10, 2019; 3:15 PM – 3:45 PM

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  Thursday, January 10, 2019; 3:15 PM – 3:45 PM

  Course Overview
  

  Goal, organization, student projects, grading, substantive snapshot.

  Faculty:  Elliot Marseille
  

  Location:  Mission Hall 1407

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• Select section Thursday, January 10, 2019; 3:45 PM – 5:00

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  Thursday, January 10, 2019; 3:45 PM – 5:00

  Core lecture 1: Decision Analysis & steps
  

  Purpose and indications for decision analysis; Steps -- formal question, decision trees, probabilities, outcomes, sensitivity analysis.

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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  • Select activity DCEA19 - Lecture 1 Decision analysis 10-Jan-2019

    

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  • Select activity Sox HC et al Expected Value Decision Making Ch 6 in Sox HC et al--Medical Decision Making 1988

    

    Sox HC et al Expected Value Decision Making Ch 6 in Sox HC et al--Medical Decision Making 1988 File
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• Select section Thursday, January 17, 2019; 3:15 PM – 4:00 PM

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  Thursday, January 17, 2019; 3:15 PM – 4:00 PM

  Lecture: Software Tutorials

  Faculty:  Elliot Marseille/Ammar Asban
  Location:  Marseille Excel MH 1407, Asban TreeAge MH 1406

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  • Select activity CEA approaches and ICERs

    

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• Select section Thursday, January 17, 2019; 4:00 PM – 5:00 PM

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  Thursday, January 17, 2019; 4:00 PM – 5:00 PM

  Small Group Discussion Section 1: Decision analysis (trees)

  Faculty: Elliot Marseille, JIm Kahn 
  
  Location: Kahn  MH 1407, Marseille MH 1406

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  • Select activity Detsky Part1 Primer Medical Decision-Making Getting started

    

    Detsky Part1 Primer Medical Decision-Making Getting started File
  • Select activity Detsky Part2 Primer Medical Decision-Making Building a tree

    

    Detsky Part2 Primer Medical Decision-Making Building a tree File
  • Select activity Detsky-Naglie Part3 Primer Medical Decision-Making Est Probs and Utilities

    

    Detsky-Naglie Part3 Primer Medical Decision-Making Est Probs and Utilities File
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  • Select activity DCEA19 decision tree templates v2

    

    DCEA19 decision tree templates v2 File
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    DCEA19 HW1 Assignment File
• Select section Thursday, January 24, 2019; 3:15 PM – 4:15 PM

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  Thursday, January 24, 2019; 3:15 PM – 4:15 PM

  Core Lecture 2: Health Outcomes (QALYs, DALYs)
  Specification, measurement, calculation, and incorporation of health status indicators. Discounting.

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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  • Select activity DCEA19 Lecture 2 Utility QALYs DALYs Discounting-24-Jan-2019

    

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  • Select activity DALYs and QALYs

    

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  • Select activity DCEA19 Lecture 2 notes QALYs DALYs discounting

    

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  • Select activity Shlipak MG Decision Analysis Ch 2 in Friedland DJ et al--Evidence-Based Medicine 1998

    

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  • Select activity Murray Lancet2012 DALYs 219 countries GBD 2010

    

    Murray Lancet2012 DALYs 219 countries GBD 2010 File
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  • Select activity DCEA15 Lecture 2 The DALYs Show-EAM ver2

    

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  • Select activity DCEA19 QALYs DALYs discounting template

    

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• Select section Thursday, January 24, 2019; 4:15 PM – 5:00 PM

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  Thursday, January 24, 2019; 4:15 PM – 5:00 PM

  Lecture: Special Topics: HIV prevention cost-effectiveness
  CEA of two interventions in global health context - female condom and pMTCT

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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  • Select activity CEA of 2 HIV nterventions_DCEA 2019

    

    CEA of 2 HIV nterventions_DCEA 2019 File
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• Select section Thursday, January 31, 2019; 3:15 PM – 3:45 PM

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  Thursday, January 31, 2019; 3:15 PM – 3:45 PM

  Small Group Discussion Section 2: Health Outcomes (QALYs, DALYs)

  Faculty:  Elliot Marseille
  
  Location: Marseille MH 1406

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  • Select activity DCEA19 Lecture 2 notes QALYs DALYs discounting

    

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• Select section Thursday, January 31, 2019; 3:45 PM – 5:00 PM

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  Thursday, January 31, 2019; 3:45 PM – 5:00 PM

  Core Lecture 3: Cost Effectiveness
  Conceptual approach to CEA. Incorporation of costs into the analysis, calculation of the incremental cost-effectiveness ratio (ICER).

  Faculty:  Elliot Marseile
  
  Location:  Mission Hall 1407

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  • Select activity DCEA19 Lecture 3 CEA 31-Jan-2019

    

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  • Select activity Timing in CEAs

    

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  • Select activity Decision Trees for CEAs

    

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  • Select activity DCEA19 Lecture 3 notes cost-effectivenes

    

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• Select section Thursday, February 7, 2019; 3:15 PM – 4:00 PM

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  Thursday, February 7, 2019; 3:15 PM – 4:00 PM

  Group Discussion Section 3: Cost-Effectiveness

  Faculty:  Elliot Marseille
  
  Location: Marseille MH 1406

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  • Select activity DCEA19 HW3 Assignment

    

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  • Select activity DCEA19 Mammog HW3

    

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• Select section Thursday, February 7, 2019; 4:00 PM – 5:00 PM

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  Thursday, February 7, 2019; 4:00 PM – 5:00 PM

  Lecture: Special Topic: Cost-Effectiveness Thresholds
  Critique of WHO thresholds and the way forward

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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  • Select activity CEA Thresholds Feb 7 2019

    

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• Select section Thursday, February 14, 2019; 3:15 PM – 4:00 PM

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  Thursday, February 14, 2019; 3:15 PM – 4:00 PM

  Core lecture 4: Data inputs

  General approach (base case, range); Health inputs (health outcomes, population traits, hierarchy of evidence); Cost inputs (direct, time); Presentation.

  Faculty:  Jim Kahn
  
  Location:  Mission Hall 1407

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  • Select activity US Preventive Services Task Force Methodology Ch 2 in USPSTF Guide to Clinical Preventative Services 1996

    

    US Preventive Services Task Force Methodology Ch 2 in USPSTF Guide to Clinical Preventative Services 1996 File
• Select section Thursday, February 14, 2019; 4:00 PM – 5:00 PM

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  Thursday, February 14, 2019; 4:00 PM – 5:00 PM

  Project Consultations

  Faculty:  Elliot Marseille and Jim Kahn
  
  Location:  Mission Hall 1407
• Select section Thursday, February 21, 2019; 3:15 PM – 3:45 PM

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  Thursday, February 21, 2019; 3:15 PM – 3:45 PM

  Group Discussion Section 4: Data Inputs

  Faculty:  Jim Kahn, Elliot Marseille
  
  Location:  Kahn MH 1407,  Marseille MH 1406

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  • Select activity DCEA19 Section 5 HW assignment cost efficacy review

    

    DCEA19 Section 5 HW assignment cost efficacy review File
• Select section Thursday, February 21, 2019; 3:45 PM – 5:00 PM

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  Thursday, February 21, 2019; 3:45 PM – 5:00 PM

  Core Lecture 5: Sensitivity Analysis
  Lecture Description: Types of uncertainty; Deterministic SA (one-way, multi-way, scenario); Probabilistic SA (reasons for, data needs, methods); Uses (planning, checking, thresholds, policy.)

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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• Select section Thursday, February 28, 2019; 3:15 PM – 4:00 PM

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  Thursday, February 28, 2019; 3:15 PM – 4:00 PM

  Group Discussion Section 5:  Sensitivity Analysis

  Faculty: Elliot Marseille
  
  Location:  Kahn MH 1407

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• Select section Thursday, February 28, 2019; 4:00 PM – 5:00 PM

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  Thursday, February 28, 2019; 4:00 PM – 5:00 PM

  Office Hours: Project Consultations
  
  

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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• Select section Thursday, March 7, 2019; 3:15 PM – 4:00 PM

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  Thursday, March 7, 2019; 3:15 PM – 4:00 PM

  Core Lecture 6: Markov Disease State Modeling
  Uses and design of portrayal of disease states in decision trees.

  Faculty:  Elliot Marseille
  
  Location: Mission Hall 1407

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• Select section Thursday, March 7, 2019; 4:00 PM - 5:00 PM

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  Thursday, March 7, 2019; 4:00 PM - 5:00 PM

  Lecture: The ethical foundations of  CEA
  

  Utilitarian and competing ethical principles. 

  Faculty:  Elliot Marseille

  Location:   Mission Hall 1407

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• Select section Thursday, March 14, 2019; 3:15 PM – 4:15 PM

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  Thursday, March 14, 2019; 3:15 PM – 4:15 PM

  Group Discussion Section 6: Markov Modeling

  Faculty:  Elliot Marseille
  
  Location:  Kahn MH 1407,  Marseille MH 1406

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• Select section Thursday, March 14, 2019; 4:15 PM - 5:00 PM

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  Thursday, March 14, 2019; 4:15 PM - 5:00 PM

  Office Hours: Article review
  
  

  Faculty:  Elliot Marseille
  
  Location:  Mission Hall 1407

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  • Select activity Lindfors KK et al CE of Mammo Screening Strategies In JAMA 20Sept1995 ocr

    

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• Select section Thursday, March 21, 2019; 3:15 PM – 5:00 PM

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  Thursday, March 21, 2019; 3:15 PM – 5:00 PM

  Lecture:  Iron CEA America

  Fun team competition -- with apologies to Iron Chef America

  Faculty:  Elliot Marseille / Jim Kahn

  Location:  Mission Hall 1407