Section outline

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  • Thursday, January 7, 2021; 3:15 PM – 5:00 PM

    Course Overview

    Goal, organization, student projects, grading, substantive snapshot.

    Core Lecture 1: Decision Analysis

    Purpose and indications for decision analysis; Steps -- formal question, decision trees, probabilities, outcomes, sensitivity analysis.

    Faculty:  Elliot Marseille

    Location (Access restricted to registered students): Zoom URL

    • Course Introduction video URL
      This video is from 2019. The schedule presented here has changed a little, but otherwise it still provides good orientation.

    • Session Slides:

    • Course Overview File
    • Lecture 1 - Decision Analysis File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 1 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only
    • CEA Purpose URL
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 1 Notes File
    • Sox HC et al Expected Value Decision Making Ch 6 in Sox HC et al--Medical Decision Making 1988 File

    • Assignment: HW1

    • HW1 Assignment File
    • HW1 example solution File
      Not available unless: You belong to Registered Students Only

    • Assignment Due Date: Thursday, January 21 at 3:15 PM

    • Turn in HW1 - Mammography (all students) Assignment
      Students must
      Make a submission
    • Course Introduction video URL
      This video is from 2019. The schedule presented here has changed a little, but otherwise it still provides good orientation.

    • Session Slides:

    • Course Overview File
    • Lecture 1 - Decision Analysis File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 1 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only
    • CEA Purpose URL
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 1 Notes File
    • Sox HC et al Expected Value Decision Making Ch 6 in Sox HC et al--Medical Decision Making 1988 File

    • Assignment: HW1

    • HW1 Assignment File
    • HW1 example solution File
      Not available unless: You belong to Registered Students Only

    • Assignment Due Date: Thursday, January 21 at 3:15 PM

    • Turn in HW1 - Mammography (all students) Assignment
      Students must
      Make a submission

  • Thursday, January 14, 2021; 3:15 PM – 5:00 PM

    Lecture: Software Tutorials
    Group Discussion: Decision analysis (trees)

    Faculty:  Elliot Marseille/Albert Young

    Location (Access restricted to registered students): Zoom URL

  • Thursday, January 21, 2021; 3:15 PM – 5:00 PM

    Core Lecture 2: Health Outcomes (QALYs, DALYs)
    Specification, measurement, calculation, and incorporation of health status indicators. Discounting.

    Lecture: Special Topic: HIV prevention cost-effectiveness

    CEA of two interventions in global health context - female condom and pMTCT

    Faculty:  Elliot Marseille

    Location (Access restricted to registered students): Zoom URL

  • Thursday, January 28, 2021; 3:15 PM – 5:00 PM

    Core Lecture 3: Cost-Effectiveness
    Conceptual approach to CEA. Incorporation of costs into the analysis, calculation of the incremental cost-effectiveness ratio (ICER).

    Faculty:  Elliot Marseile

    Location (Access restricted to registered students):     Zoom URL

    • Session Slides:

    • DCEA Lecture on cost-effectivenss analysis File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 3 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only
    • Timing in CEAs URL
      Not available unless: You belong to Registered Students Only
    • CEA Research Questions URL
      Not available unless: You belong to Registered Students Only
    • Decision Trees for CEAs URL
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 3 Notes - Cost-effectiveness File
    • Salomon_disability_weight_GBD_2010_Lancet_2013 File
    • Jonsson Ten Arguments Societal Perspective 2009 File
    • Jamison File
      Not available unless: Your ID number contains 02
    • Kahn File
      Not available unless: Your ID number contains 02
    • Russell File
      Not available unless: Your ID number contains 02

    • Assignment: HW3

    • HW3 Assignment File
    • DCEA_Mammog_HW3.xls File

    • Assignment Due Date:  Thursday, February 4 at 3:15 PM

    • Turn in HW3 - Mammography (all students) Assignment
      Students must
      Make a submission

    • Session Slides:

    • DCEA Lecture on cost-effectivenss analysis File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 3 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only
    • Timing in CEAs URL
      Not available unless: You belong to Registered Students Only
    • CEA Research Questions URL
      Not available unless: You belong to Registered Students Only
    • Decision Trees for CEAs URL
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 3 Notes - Cost-effectiveness File
    • Salomon_disability_weight_GBD_2010_Lancet_2013 File
    • Jonsson Ten Arguments Societal Perspective 2009 File
    • Jamison File
      Not available unless: Your ID number contains 02
    • Kahn File
      Not available unless: Your ID number contains 02
    • Russell File
      Not available unless: Your ID number contains 02

    • Assignment: HW3

    • HW3 Assignment File
    • DCEA_Mammog_HW3.xls File

    • Assignment Due Date:  Thursday, February 4 at 3:15 PM

    • Turn in HW3 - Mammography (all students) Assignment
      Students must
      Make a submission

  • Thursday, February 4, 2021; 3:15 PM – 5:00 PM

    Obtaining Input Data and In-Class Journal Club 

    Core Lecture 4: Data inputs (Faculty: Jim Kahn)

    General approach (base case, range); Health inputs (health outcomes, population traits, hierarchy of evidence); Cost inputs (direct, time); Presentation.

    Location:  Zoom URL

  • Thursday, February 11, 2021; 3:15 PM – 5:00 PM

    Core Lecture 5: Markov Disease State Modeling
    Uses and design of portrayal of disease states in decision trees.

    Faculty:  Elliot Marseille

    Location:     Zoom URL

    • Session Slides:

    • Lecture 5 - Markov and CEA of MDMA to treat PTSD File
    • MAPS CEA of MDMA for PTSD File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 5 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 5 Notes - Markov File
    • Naimark D et al Primer on Medical DA--Part 5--Working with Markov Processes In Med Decis Making Apr-Jun 1997 File
      Not available unless: Your ID number contains 02
    • Nutt Current status of psychedelics in psychiatry 2020.pdf File

    • Assignment: HW5

    • HW 5 Assignment (choose either 5A or 5B) File
    • Revised Markov template File
    • DCEA21_HW5_Markov.trex (for HW 5B) File

    • Assignment Due Date: Thursday, February 18 at 3:15 PM

    • Turn in HW5 (2-credit track only) Assignment
      Students must
      Make a submission

    • If you are in the 3-credit track, submit your HW 5 assignment by emailing it to emarseille@comcast.net

    • Tool Files:

    • Session Slides:

    • Lecture 5 - Markov and CEA of MDMA to treat PTSD File
    • MAPS CEA of MDMA for PTSD File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 5 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 5 Notes - Markov File
    • Naimark D et al Primer on Medical DA--Part 5--Working with Markov Processes In Med Decis Making Apr-Jun 1997 File
      Not available unless: Your ID number contains 02
    • Nutt Current status of psychedelics in psychiatry 2020.pdf File

    • Assignment: HW5

    • HW 5 Assignment (choose either 5A or 5B) File
    • Revised Markov template File
    • DCEA21_HW5_Markov.trex (for HW 5B) File

    • Assignment Due Date: Thursday, February 18 at 3:15 PM

    • Turn in HW5 (2-credit track only) Assignment
      Students must
      Make a submission

    • If you are in the 3-credit track, submit your HW 5 assignment by emailing it to emarseille@comcast.net

    • Tool Files:

  • Thursday, February 18, 2021; 3:15 PM – 5:00 PM

    Core Lecture 6: Sensitivity Analysis
    Lecture Description: Types of uncertainty; Deterministic SA (one-way, multi-way, scenario); Probabilistic SA (reasons for, data needs, methods); Uses (planning, checking, thresholds, policy.)

    Faculty:  Elliot Marseille

    Location:      Zoom URL

    • Session Slides:

    • Lecture 6 - Sensitivity analysis File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 6 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only
    • Sensitivity Analyses URL
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 6 Notes - Sensitivity Analysis File
    • Krahn MD Primer on Med DA--Part 4--Analyzing the Model Interpreting the Results Med Decis Making Apr-Jun 1997 File
      Not available unless: Your ID number contains 02

    • Assignment: HW6

    • HW6 Assignment File
    • DCEA_Mammog_HW6 File
    • DCEA what-if-analysis data table for sensitivity analysis v2 File

    • Assignment Due Date: Thursday, February 25 at 3:15 PM

    • Turn in HW6 - Mammography (all students) Assignment
      Students must
      Make a submission

    • Session Slides:

    • Lecture 6 - Sensitivity analysis File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 6 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only
    • Sensitivity Analyses URL
      Not available unless: You belong to Registered Students Only

    • Required Reading:

    • Lecture 6 Notes - Sensitivity Analysis File
    • Krahn MD Primer on Med DA--Part 4--Analyzing the Model Interpreting the Results Med Decis Making Apr-Jun 1997 File
      Not available unless: Your ID number contains 02

    • Assignment: HW6

    • HW6 Assignment File
    • DCEA_Mammog_HW6 File
    • DCEA what-if-analysis data table for sensitivity analysis v2 File

    • Assignment Due Date: Thursday, February 25 at 3:15 PM

    • Turn in HW6 - Mammography (all students) Assignment
      Students must
      Make a submission

  • Thursday, February 25, 2021; 3:15 PM – 5:00 PM

    Core Lecture 7: Cost-Effectiveness Thresholds
    Critique of WHO thresholds and the way forward

    Faculty:  Elliot Marseille

    Location:      Zoom URL

    • Lecture 7 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only

    • Session Slides:

    • Lecture 7 - Cost-effectiveness thresholds File

    • Session Audio/Video Recording (Access restricted to registered students):

    • CEA Results Table URL
      Not available unless: You belong to Registered Students Only
    • Lecture 7 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only

    • Session Slides:

    • Lecture 7 - Cost-effectiveness thresholds File

    • Session Audio/Video Recording (Access restricted to registered students):

    • CEA Results Table URL
      Not available unless: You belong to Registered Students Only

  • Thursday, March 4, 2021; 3:15 PM – 5:00 PM

    Lecture: Special Topic: Ethics of Cost-Effectiveness

    Utilitarian and competing ethical principles.

    Faculty: Elliot Marseille

    Location:  Zoom URL

    • Lecture 8 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only

    • Session Slides:

    • Lecture 8.1 - Ethical Foundations of CEA File
    • Lecture 8.2 - Equity efficiency and the SW quadrant File

    • Session Audio/Video Recording (Access restricted to registered students):

    • CEA Next Steps URL
      Not available unless: You belong to Registered Students Only
    • Lecture 8 zoom recording Media Resource
      Not available unless: You belong to Registered Students Only

    • Session Slides:

    • Lecture 8.1 - Ethical Foundations of CEA File
    • Lecture 8.2 - Equity efficiency and the SW quadrant File

    • Session Audio/Video Recording (Access restricted to registered students):

    • CEA Next Steps URL
      Not available unless: You belong to Registered Students Only

  • Thursday, March 11, 2021; 3:15 PM – 5:00 PM

    Article Review

    Location:  Zoom URL

  • Thursday, March 18, 2021; 3:15 PM - 5:00 PM

    Iron CEA America

    Fun team competition -- with apologies to Iron Chef America

    Faculty:  Elliot Marseille / Jim Kahn

    Location:  Zoom only

    • Session Materials:

    • Iron CEA America File
    • Iron CEA start File
    • Lindfors KK et al CE of Mammo Screening Strategies In JAMA 20Sept1995 ocr File
      Not available unless: Your ID number contains 02

    • Session Materials:

    • Iron CEA America File
    • Iron CEA start File
    • Lindfors KK et al CE of Mammo Screening Strategies In JAMA 20Sept1995 ocr File
      Not available unless: Your ID number contains 02