BIOSTAT 200: Biostatistical Methods for Clinical Research I (Fall 2014)
Section outline
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BIOSTATISTICAL METHODS FOR CLINICAL RESEARCH I
BIOSTAT 200 Fall 2014 (3 units).
Course Director: Judy Hahn, PhD, MA.
Associate Professor, Department of Medicine -
Assignments Folder
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The final exam is due by December 11 at 10:30 AM.
You will need to log into the CLE to be able to upload your assignment. Please upload as a .pdf such that all your formatting will be preserved.
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Lecture: Orientation to Biostat 200, types of statistical variables, and univariate data summary
This lecture will include an overview of the course and expectations. Introduction to descriptive statistical analysis including definition of different types of variables, construction of frequency tables, measures of centrality (means, median, mode, range), standard deviation, and graphs (histograms, box plots, scatter plots, line graphs).Faculty: Judith Hahn
Location: China Basin 6702 -
Office Hours
Faculty: Judith Hahn
Location: China Basin 6702 -
Computer Lab
Review of previous lecture and assigned materialFaculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Location: CB 6702 -
Lecture: Data cleaning and basic probablility concepts
This lecture will provide the basic probability terms and probability statements needed as a foundation for more advance statistical concepts. We will discuss the meaning of theoretical statistical distributions and examine the binomial distribution.Faculty: Judith Hahn
Location: China Basin 6702 -
Office Hours
Faculty: Judith Hahn
Location: China Basin 6702 -
Lecture: Theoretical probability distributions (binomial and normal)
This lecture will build on the concepts of probability and discuss the properties of the binomial and normal distributions.Faculty: Judith Hahn
Location: China Basin 6702 -
Office Hours
Faculty: Judith Hahn
Location: China Basin 6702 -
Computer Lab
Faculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Review of previous lecture and assigned material
Location: CB 6702 -
Lecture: Sampling distribution and confidence intervals
This lecture will discuss the concept of sampling, of sampling distributions, and the central limit theorem. We will use the central limit theorem to derive confidence intervals for means and proportions.Faculty: Judith Hahn
Location: China Basin 6702 -
Office Hours
Faculty: Judith Hahn
Location: China Basin 6702 -
Computer Lab
Faculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Review of previous lecture and assigned material
Location: CB 6702 -
Lecture: Hypothesis testing, comparison of one mean and on proportion
This lecture will also introduce hypothesis testing and the associated terminology for one-sided and two-sided hypothesis tests. This lecture will demonstrate hypothesis testing of one mean and one proportion.Faculty: Judith Hahn
Location: China Basin 6702 -
Office Hours
Faculty: Judith Hahn
Location: China Basin 6702 -
Computer Lab
Faculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Review of previous lecture and assigned material
Location: CB 6702 -
Lecture: Comparison of two means, two proportions, and multiple means
In this lecture we will extend hypothesis testing to the comparison of two means and two proportions.Faculty: Judith Hahn
Location: Mission Hall 1400 -
Office Hours
Faculty: Judith Hahn
Location: Mission Hall 1400 -
Computer Lab
Faculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Review of previous lecture and assigned material
Location: MH 1400 -
Lecture: Analysis of variance, nonparametric testing, and review of hypothesis testing
In this lecture we will discuss analysis of variance to compare multiple means, as well as non-parametric tests including the sign test, the Wilcoxon signed-rank test, and the Wilcoxon rank sum test. We will also review the hypothesis testing methods that we have covered in prior lectures.
Faculty: Judith Hahn
Location: Mission Hall 1400 -
Office Hours
Faculty: Judith Hahn
Location: MH 1400 -
Computer Lab
Review of previous lecture and assigned materialFaculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Location: MH 1400 -
Lecture: Contingency tables, McNemar's test, relative risks, and odds ratios
In this lecture we will discuss the construction of contingency tables and learn the chi-square test for independence for examining categorical data. We will start with 2x2 tables and move to larger tables, and we will discuss relative risks and odds ratios and calculate confidence intervals for these measures. We will discuss the use of McNemar’s test to examine paired dichotomous data.Faculty: Judith Hahn
Location: Mission Hall 1400 -
Office Hours
Faculty: Judith Hahn
Location: MH 1400 -
Computer Lab
Review of previous lecture and assigned materialFaculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Location: MH 1400 -
Lecture: Correlation and simple linear regression
In this lecture we will define and show the calculation for Pearson and Spearman correlation coefficients and introduce the simple linear regression model.
Faculty: Judith Hahn
Location: Mission Hall 1400 -
Office Hours
Faculty: Judith Hahn
Location: MH 1400 -
Computer Lab
Review of previous lecture and assigned materialFaculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Location: MH 1400 -
Lecture: Simple linear regression and multiple linear regression
In this lecture we will introduce prediction intervals, regression diagnostics, and transformations as well as multiple linear regression.
Faculty: Judy Hahn
Location: Mission Hall 1400 -
Office Hours
Faculty: Judith Hahn
Location: MH 1400 -
Lecture: Multiple linear regression and logistic regression
In this lecture we will continue the topic of multiple linear regression and introduce logistic regression. We will discuss the model and interpretation of the parameters.Faculty: Judy Hahn
Location: Mission Hall 1400 -
Office Hours
Faculty: Judith Hahn
Location: MH 1400 -
Computer Lab
Review of previous lecture and assigned materialFaculty: Judith Hahn, Gabriel Brooks, Vasantha Jotwani, Elaine Ku, Annie Narla, Aaron Spicer
Location: MH 1400 -
Office Hours
Faculty: Judith Hahn
Location: MH 1400