Section outline

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  • Friday, January 13, 2017; 1:30 PM - 3:00 PM

    Lecture: Introduction: Causal theories and interrelationships between measures of disease occurrence

    Theories of causal inference
    Causal models and heuristics
    Counterfactual effect measures

     

    Faculty:  Lydia B. Zablotska

    Location:      Mission Hall 1407

    • Prospectus:

    • Syllabus Epi Methods II Winter 2017 File
    • Course Introduction EPI 207 Winter 2017 File
    • Course Introduction Video URL

    • Session Slides:

    • Week #1 slides, revised after class on 01.20.2017 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      Rothman, Greenland and Lash 2008 (RGL2008) Chs 2, 4, 12

    • Recommended Reading:

      Rothman 2012 (R2012) Chs 1-3

    • Cole and Frangakis 2009 File
      Not available unless: Your ID number contains 02

    • Introduction to CAP dataset:

    • Fradet Dietary omega-3 and prostate cr Clin Cancer Res 2009 File
      Not available unless: Your ID number contains 02
    • Intro to CAP dataset review Stata File
    • Intro_to_CAP dataset for STATA users File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignment:

    • Jain MMR ASD JAMA 2015 File
      Not available unless: Your ID number contains 02
    • Orr ABM JECH 2016 File
      Not available unless: Your ID number contains 02
    • Homework for Week #1 File
      Not available unless: Your ID number contains 02
    • Week #1 Homework Submission Assignment

      Submit your assignment here. Deadline is 01/20/2017 at 1PM.

      Available until January 20 2017, 1:00 PM
    • Sign up to present your work-in-progress Forum

      Student oral presentations of research-in-progress:

      Please let us know if you would like to make a short presentation about your research project in-progress during the week when we are covering topics of interest to you.  There is no better way to learn the theoretical material than to work on an actual project.  And, as a bonus, you will get feedback from the whole class and might even find a collaborator!

      General guidelines:

      Choose a week when we will be discussing a topic of interest to you.  Let us know about it in advance.  Prepare a short 5-min presentation of project in-progress during the week when we are covering topics of interest to you and formulate 2-3 questions for the class.

      Best student presentation wins a prize!

      Why should you consider doing this:

      1. You get extra points on your final grade.
      2. There is no better way to learn the theoretical material than to work on an actual project. 
      3. You will get feedback from the whole class and might even find a collaborator!

      Best student presentation wins a prize! At the end of the course we will select the best presentation by popular vote. The winner will receive an excellent book by R. E. Harris, Epidemiology of Chronic Disease: Global Perspectives.

  • Friday, January 20, 2017; 1:30 PM - 3:00 PM

    Lecture: Directed Acyclic Graphs (DAGs) and causal structures of different types of biases  

    Intro to causal inference; causal DAGs; DAGs and confounding; DAGs and selection bias.

    Faculty:  Cindy Leung

    Location:      Mission Hall 1407

    • Session slides:

    • Week #2 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      RGL 2008 Ch 12

      H&R 2015 Ch 6

    • Recommended Reading:

               H&R 2015 Ch7-9

    • Weng and Hertz-picciotto 2009 File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignments:

    • Homework for Week #2 File
      Not available unless: Your ID number contains 02
    • Le-Scherban Schooling AJE 2014 File
      Not available unless: Your ID number contains 02
    • Chen Obesity PD AJE 2004 File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (access restricted to registered students):

  • Friday, January 27, 2017; 1:30 PM - 3:00 PM

    Lecture: Observational Study Designs I
    Classifications of observational study designs, field methods for observational study designs, introduction to instrumentation and data collection methods, design features of cohort studies

    Faculty: Lydia Zablotska
     
    Location:      Mission Hall 1407

    • Session Slides:

    • Week #3 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      RGL 2008 Ch 6
      RGL 2008 Ch 7
      RGL 2008 Ch 24
      SNC 2015 Ch 6
      SNC 2015 Ch 13

    • SNC Ch 6 File
      Not available unless: Your ID number contains 02
    • SNC Ch13 File
      Not available unless: Your ID number contains 02

    • Recommended Reading:

      H&R2015 Ch 3

    • H&R2015 Part I, Ch 3 File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignments:

    • Homework for Week #3 File
      Not available unless: Your ID number contains 02
    • Vidal CHO PC Prostate 2015 File
      Not available unless: Your ID number contains 02

    • CAP dataset files:

    • CAP dataset File
      Not available unless: Your ID number contains 02
    • dataset codebook File
      Not available unless: Your ID number contains 02
    • CAP dataset for STATA users - STATA File
    • Week #3 Homework Submission Assignment

      Submit your homework for week #3. Deadline at 1PM on 2/3/2017.

      Available until February 3 2017, 1:00 PM

    • Assignment Answer Key (access restricted to registered students):

  • Friday, February 3, 2017; 1:30 PM - 3:00 PM

    Lecture: Observational study designs II

    Design features of case-control studies, special types of case-control studies

    Faculty:  Lydia Zablotska

    Location:      Mission Hall 1407

    • Session Slides:

    • Week #4 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      RGL2008 Ch 8 (pp111-124),

    • Recommended Reading:

      H&R2015 Ch 3

    • H&R2015 Part I, Ch 3 File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignments:

    • Homework for Week #4 File
      Not available unless: Your ID number contains 02
    • Schernhammer Shift Work AJE 2013 File
      Not available unless: Your ID number contains 02
    • Week #4 Homework Submission Assignment

      Submit your homework for week #4. Deadline at 1PM on 2/10/2017.

      Available until February 10 2017, 1:00 PM

  • Friday, February 10, 2017; 1:30 PM - 3:00 PM

    Lecture: Observational study designs III

    Less commonly used observational study designs, ecological and cross-sectional studies, surveys, case-only, case-crossover, case-time-control, special-exposure cohorts

    Faculty:  Lydia Zablotska

    Location:      Mission Hall 1407

    • Session Slides:

    • Week #5 slides File
    • OPTIONAL: Genetic study designs by L. Hindorff File
      Not available unless: Your ID number is 02

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      RGL2008 Ch 8 (pp 125-127)
      RGL2008 Ch 22 (pp 472-476)
      RGL2008 Ch 25
      RGL2008 Ch 28 (pp 573-575)

      RGL2008 Ch 30 (pp 605-606)

    • Optional Reading:

    • Discussion section readings and homework assignments:

    • Homework for Week #5 File
      Not available unless: Your ID number contains 02
    • Basu Ecological study PLoS One 2013 File
      Not available unless: Your ID number contains 02
    • Dufault and Klar 2011 File
      Not available unless: Your ID number contains 02
    • Gillespie Case-chaos studies AJE 2012 File
      Not available unless: Your ID number contains 02
    • Edelstein et al and McCarthy et al response 2014 File
      Not available unless: Your ID number contains 02
    • Mostofsky Anger MI AJC 2013 File
      Not available unless: Your ID number contains 02
    • Stang and Jockel 2004 File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (access restricted to registered students):

  • Friday, February 17, 2017; 1:30 PM - 3:00 PM

    Lecture: Measurement theory and practice I

    Standardized approaches to measurement, methods of test development I: Item response theory, item analysis, scaling and factor analysis; Methods of test development II: Instrumental design, construction and interpretation in cross-cultural situations

    Faculty: Lydia Zablotska 

    Location:      Mission Hall 1407

    • Session Slides:

    • Week #6 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      SNC 2015 Ch 8-10

    • SNC Ch 8 File
      Not available unless: Your ID number contains 02
    • SNC Ch 10 File
      Not available unless: Your ID number contains 02

    • Recommended Reading:

      RGL 2008 Ch 9-10

    • SNC Ch 9 File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignments:

    • Homework for Week #6 File
      Not available unless: Your ID number contains 02
    • DeVon et al. 2007 File
      Not available unless: Your ID number contains 02
    • Goodwin 2002 File
      Not available unless: Your ID number contains 02
    • Higgins and Straub 2006 File
      Not available unless: Your ID number contains 02

    • Stata Tutorials:

    • Factor Analysis File

    • Data Files:

    • W#7 FA dataset File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (access restricted to registered students):

  • Friday, February 24, 2017; 1:30 PM - 3:00 PM

    In-class closed book quiz (1:30-2:00 pm) - REQUIRED.

    Lecture: Measurement theory and practice II

    Overview of measurement theory, reliability and validity in epidemiological studies, study design features affecting precision of results, including effects of multiple comparisons, methods of sampling and estimation of sample size and statistical power

    Faculty:  Lydia Zablotska

    Location:  Mission Hall 1407

    • Session Slides:

    • Week #7 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      SNC Ch 3-5, 7, 12, 14

    • SNC Ch 3 File
      Not available unless: Your ID number contains 02
    • SNC Ch 4 File
      Not available unless: Your ID number contains 02
    • SNC Ch 5 File
      Not available unless: Your ID number contains 02
    • SNC Ch 7 File
      Not available unless: Your ID number contains 02
    • SNC Ch 12 File
      Not available unless: Your ID number contains 02
    • SNC Ch 14 File
      Not available unless: Your ID number contains 02

    • Recommended Reading:

      RGL 2008 Ch 9-10

    • Keszei-Novak -Streiner-scales intro-2010 File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignments:

    • Stata Tutorials:

    • ICC File
    • Cronbach's alpha File
    • Cohen's kappa File

    • Homework and homework datasets:

    • Week #7 Homework File
      Not available unless: Your ID number contains 02
    • Messer NDI JUH 2006 File
      Not available unless: Your ID number contains 02
    • CHIS File
      Not available unless: Your ID number contains 02
    • ICC missing File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (access restricted to registered students):

  • Friday, March 3, 2017; 1:30 PM - 3:00 PM

    Lecture: Confounding

    Measured and unmeasured confounding; instrumental variables and propensity scores.

    Faculty:  Lydia Zablotska

    Location:      Mission Hall 1407

    • Session Slides:

    • Week #8 slides File
    • Week 8 - Test your knowledge of confounding File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      RGL2008 Ch 9 (pp 129-134)
      RGL2008 Ch 12
      RGL2008 Ch 15

    • Recommended Reading:

      R2012 Ch 10

      H&R 2015 Ch 7

    • Discussion section readings and homework assignments:

    • Week #8 Homework File
      Not available unless: Your ID number contains 02
    • Kurth et al 2005 File
      Not available unless: Your ID number contains 02
    • Hernan et al 2002 File
      Not available unless: Your ID number contains 02
    • Howards Use of DAGs and causality AJE 2012 File
      Not available unless: Your ID number contains 02
    • CHIS File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (access restricted to registered students):

  • Friday, March 10, 2017; 1:30 PM - 3:00 PM

    Lecture: Interaction and effect-measure modification I

    Biological vs. statistical; multiplicative and additive; evaluation of interaction, presentation of results.

    Faculty:  Cindy Leung
     
    Location:      Mission Hall 1407

    • Session Slides:

    • Week #9 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Theoretical and Conceptual Frameworks

    • VanderWeele Vansteelandt AJE 2014 File
      Not available unless: Your ID number contains 02
    • Zhang Am. J. Epidemiol. 2011 File
      Not available unless: Your ID number contains 02
    • VanderWeele-396-9 AJE mechanisticIx File
      Not available unless: Your ID number contains 02
    • Knol VanderWeele Int. J. Epidemiol. 2012 File
      Not available unless: Your ID number contains 02

    • Required Reading:

      RGL2008 Ch 5
      RGL2008 Ch 16

    • HR Ch 4-5 File
      Not available unless: Your ID number contains 02

    • Recommended Reading:

      R2012 Ch 11

    • Discussion section readings and homework assignments:

    • Week #9 Homework File
    • Interaction File
    • delta method File
    • Knol et al 2007 File
      Not available unless: Your ID number contains 02
    • RERI calculations rev File
      Not available unless: Your ID number contains 02
    • Turner et al Am. J. Epidemiol. 2014 File
      Not available unless: Your ID number contains 02
    • Week #9 Homework Submission Assignment
      Available until March 17 2017, 1:00 PM

    • Assignment Answer Key (access restricted to registered students):

  • Friday, March 17, 2017; 1:30 PM - 3:00 PM

    Lecture: Interaction and effect-measure modification II

    Assessment of multiplicative and additive interaction for various types of data, presentation of results of studies with interaction

    Faculty:  Cindy Leung


    Location:      Mission Hall 1407

    • Session Slides:

    • Week #10 slides File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Theoretical and Conceptual Frameworks

    • Zhang Am. J. Epidemiol. 2011 File
      Not available unless: Your ID number contains 02
    • VanderWeele Vansteelandt AJE 2014 File
      Not available unless: Your ID number contains 02
    • VanderWeele-396-9 AJE mechanisticIx File
      Not available unless: Your ID number contains 02
    • Knol VanderWeele Int. J. Epidemiol. 2012 File
      Not available unless: Your ID number contains 02

    • Required Reading:

      VW 2015 Ch 9-10

    • VW Ch 9-10 File
      Not available unless: Your ID number contains 02

    • Discussion section readings and homework assignments:

    • delta method File