EPI 214: Systematic Reviews (Spring 2019)
Section outline
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Lecture 1: Designing a Systematic Review
Indications and overview of the steps of systematic reviews, how to formulate research questions and developing a protocol, Data sources, search strategy and publication bias; inclusion and exclusion criteria, quality assessment, data abstraction forms, selection of studies, homogeneity.Faculty: Steve Bent
Location: Mission Hall 1400-
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Bent S, Shojania, K, Saint, S. The use of systematic reviews and meta-analyses in infection control and hospital epidemiology. Am J Infect Control. 2004 June:32(4):246-254. File
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Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Info Libr J. 2009. Jun;26(2):91-108. File
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Moher D, Liberati A , Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. File
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Cooke A, Smith D, Booth A. Beyond PICO: the SPIDER tool for qualitative evidence synthesis. Qual Health Res. 2012 Oct;22(10):1435-43 File
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Ioannidis - Mass Production of SR File
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Lecture 2:
Part A: 45 min: Developing a Protocol for Systematic Review
Part B: 45 min: Literature SearchFaculty: Steve Bent (Part A)/E. Whitaker (Part B)
Location: MH 1400
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Li T, et al. Innovations in data collection, management, and archiving for systematic reviews. Ann Intern Med. 2015 Feb 17;162(4):287-94. File
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Lecture 3: Analytical Methods
Faculty: Stephen Bent
Location: Mission Hall 1400-
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Moher D, Schulz KF, Altman DG. The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials. Annals of Internal Medicine. 2001;134:657-62. File
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Berlin JA, Golub RM. Meta-analysis as evidence: building a better pyramid. JAMA. 2014;312:603-5. File
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Juni et al. Hazards of scoring the quality of clinical trials for meta-analysis. JAMA. 1999;1054-60. File
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Dechartres A, Altman DG, Trinquart L, Boutron I, Ravaud P. Association between analytic strategy and estimates of treatment outcomes in meta-analyses. JAMA. 2014;312:623-30. File
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Lecture 4: Performing a Meta-analysis
Faculty: Steve Bent
Location: Mission Hall 1400
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Lecture 5: Performing a Critique of a Systematic Review: Journal Club
Faculty: Steve Bent
Location: Mission Hall 1400-
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Rowe BH et al. Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Annals of Emergency Medicine. 2000;36:181-190. File
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Alter HJ et al. Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-anlaysis. Annals of Emergency Medicine. 2000;36:191-197. File
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Lecture 6: New and Advanced Methods for Pooling Studies
Faculty: Elaine Allen
Location: MH 1400
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