Section outline

  • Lecture 1: Designing a Systematic Review
    Indications and overview of the steps of systematic reviews, how to formulate research questions and developing a protocol, Data sources, search strategy and publication bias; inclusion and exclusion criteria, quality assessment, data abstraction forms, selection of studies, homogeneity.

    Faculty: Steve Bent
     
    Location:  Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL
    • Required Reading:

    • Bent S, Shojania, K, Saint, S. The use of systematic reviews and meta-analyses in infection control and hospital epidemiology. Am J Infect Control. 2004 June:32(4):246-254. File
      Not available unless: Your ID number contains 02
    • Optional Reading:

    • Grant MJ, Booth A. A typology of reviews: an analysis of 14 review types and associated methodologies. Health Info Libr J. 2009. Jun;26(2):91-108. File
      Not available unless: Your ID number contains 02
    • Moher D, Liberati A , Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. File
      Not available unless: Your ID number contains 02
    • Cooke A, Smith D, Booth A. Beyond PICO: the SPIDER tool for qualitative evidence synthesis. Qual Health Res. 2012 Oct;22(10):1435-43 File
      Not available unless: Your ID number contains 02
    • Ioannidis - Mass Production of SR File
      Not available unless: Your ID number contains 02
    • Assignment: NO HOMEWORK to submit, Required reading as shown in Lecture 1 Prospectus.

       

  • Lecture 2:

    Part A: 45 min: Developing a Protocol for Systematic Review

    Part B: 45 min: Literature Search

    Faculty: Steve Bent (Part A)/E. Whitaker (Part B)

    Location:  MH 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL
    • Optional Reading:

    • Li T, et al. Innovations in data collection, management, and archiving for systematic reviews. Ann Intern Med. 2015 Feb 17;162(4):287-94. File
      Not available unless: Your ID number contains 02
    • Resources:

    • Assignment: Submit a DRAFT Systematic Review Protocol, 1-2 pages as described in Lecture 2 Prospectus.

    • Assignment Due Date:  April 16

  • Lecture 3: Analytical Methods

    Faculty: Stephen Bent

    Location:  
    Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL
    • Optional Reading:

    • Moher D, Schulz KF, Altman DG. The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials. Annals of Internal Medicine. 2001;134:657-62. File
      Not available unless: Your ID number contains 02
    • Berlin JA, Golub RM. Meta-analysis as evidence: building a better pyramid. JAMA. 2014;312:603-5. File
      Not available unless: Your ID number contains 02
    • Juni et al. Hazards of scoring the quality of clinical trials for meta-analysis. JAMA. 1999;1054-60. File
      Not available unless: Your ID number contains 02
    • Dechartres A, Altman DG, Trinquart L, Boutron I, Ravaud P. Association between analytic strategy and estimates of treatment outcomes in meta-analyses. JAMA. 2014;312:623-30. File
      Not available unless: Your ID number contains 02
    • Assignment: NO HOMEWORK to submit. Optional reading as shown in Lecture 3 Prospectus.

  • Lecture 4 Performing a Meta-analysis

    Faculty:  Steve Bent

    Location: Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL
    • Assignment:  April 30, STATA Problem set due

    • Datasets:

  • Lecture 5: Performing a Critique of a Systematic Review: Journal Club

    Faculty: Steve Bent

    Location:  
    Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL
    • Required Reading:

    • Rowe BH et al. Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Annals of Emergency Medicine. 2000;36:181-190. File
      Not available unless: Your ID number contains 02
    • Alter HJ et al. Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-anlaysis. Annals of Emergency Medicine. 2000;36:191-197. File
      Not available unless: Your ID number contains 02
    • Resources:

    • Assignment: May 7 homework due: 1-2 page critique of 2 systematic reviews as described in Lecture 5 Prospectus

  • Lecture 6: New and Advanced Methods for Pooling Studies

    Faculty: Elaine Allen

    Location: MH 1400