Section outline

  • BMS 214: Ethics and Responsible Conduct of Research 2015

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    BMS 214: Ethics and the Responsible Conduct of Research

    Spring 2015

     

    Faculty Director: Bruce Conklin, BConklin@gladstone.ucsf.edu

    Coordinator: Ulluminair Salim, ulluminair.salim@ucsf.edu

     

    LOCATIONS

    Wednesdays – Parnassus Health Sciences West 300 (except May 6th at Cole Hall)

    Thursdays – Mission Bay (Byers Auditorium, Genentech Hall 106)

     

    COURSE WEBSITE: https://courses.ucsf.edu/course/view.php?id=1588

    COURSE DESCRIPTION

    On behalf of the combined basic science graduate programs at UCSF, OCPD coordinates an annual course entitled "Ethics and the Responsible Conduct of Research (RCR)". This course is designated as “BMS 214” and meets the NIH requirements for training in the Responsible Conduct of Research required of all graduate students. Each Spring quarter, the course is offered at both Mission Bay and Parnassus.

    Using lecture and case study formats, this course is designed to address key issues affecting the responsible conduct of scientific research, including:

    • Scientific Misconduct: Plagiarism, Falsification and Fabrication of Data
    • Scientific Record Keeping and Data Management
    • Animals in Research: Animal Rights and Welfare
    • Human Subjects in Research
    • Publication, Responsible Authorship and Peer Review Practices
    • Conflicts of Interest
    • Mentoring and Being Mentored

    This course is required for second-year graduate students enrolled in UCSF’s basic science graduate programs. Graduate students will be prompted to register for the course by their Program Administrators.  For 2015, BMS 214 runs for 7 consecutive weeks.  Identical sessions are offered at Parnassus and Mission Bay every week.  Wednesday sections are at Parnassus, 10 am - 11:30 am beginning April 8.  Thursday sections are at Mission Bay, 10 am - 11:30 am, beginning April 9.

     

    Time policy: 10:00  – 11:30 AM  Doors close at 10:10 AM. Late arrivals will NOT be given credit for the session and will need to make up the session next year

     

    Laptop policy: This course uses lectures, case studies and group discussions to teach students about some of the most important but difficult responsible practice topics facing professional researchers.  Therefore, students are expected to be fully engaged in all class lectures and discussions, and the course organizers and directors ask you to refrain from using laptops, tablets and handhelds for personal or research-related work during class time.

     

    Sign-in policy:          You MUST Register on the course website AND sign the attendance sheet to receive credit for the session!

    In the Event of ONE Pre-approved Absence…

    Think Piece 

    In order to pass BMS 214 you must participate in all seven sessions.  However, in the event that you miss one session and have contacted your graduate program administrator in advance, you will have the opportunity to fulfill ONE such session by producing a "think piece,” thereby critically evaluating the topic as it relates to your own research experience.  The think piece should include a discussion of readings, case studies, and/or reflection on the relevance of the weekly theme for your own research. This document must be submitted to the 2015 BMS 214 Course Website Repository no later than 5pm on Thursday, May 28th.

     

    The Think Piece make-up assignment applies only to graduate students who obtain permission in advance to make-up no more than ONE pre-approved missed session

    Your pre-approved Think Piece should be 1-2 pages; double spaced; one-inch margins

     

    Steps to Take to Submit a Think Piece

    1. Obtain permission IN ADVANCE of missed session by sending a request to your program administrator and carbon copy course coordinator Ulluminair Salim.
    2. Submit pre-approved Think Piece for ONE missed session to the course website repository by 5pm on Thursday, May 28th

  • Week 1: Scientific Misconduct and Ethics in Science

    Week 1:        

    Wednesday, April 8 (Health Sciences West 300) or Thursday, April 9 (Byers Auditorium, Genentech Hall 106)

     

    Scientific Misconduct and Ethics in Science

    Bruce Conklin – Professor, Medical Genetics and Senior Investigator, Gladstone Institutes

    Developing a well-reasoned response to an ethical problem in scientific research. The meaning of research misconduct and the regulations, policies, and guidelines that govern research misconduct in PHS-funded institutions. Includes topics such as fabrication, falsification, and plagiarism; error vs. intentional misconduct; institutional misconduct policies; identifying misconduct; procedures for reporting misconduct; protection of whistleblowers; and outcomes of investigations, including institutional and federal actions.

  • Week 2: Publications and Peer Review

    Week 2:        

    Wednesday, April 15 (Health Sciences West 300) or Thursday, April 16 (Byers Aud., Genentech Hall 106)

     

    Publications and Peer Review

    Vivian Siegel – Director of Scientific Education and Public Communication, The Broad Institute

    of MIT and Harvard; Past Editor-in-Chief of Cell and of Executive Director of PLoS

    The purpose and importance of scientific publication, and the responsibilities of the authors. Includes topics such as collaborative work and assigning appropriate credit, acknowledgments, appropriate citations, repetitive publications, fragmentary publication, sufficient description of methods, corrections and retractions, conventions for deciding upon authors, author responsibilities, and the pressure to publish.  Also, the purpose of peer review in determining merit for research funding and publications.  Includes topics such as, the definition of peer review, impartiality, how peer review works, editorial boards and ad hoc reviewers, responsibilities of the reviewers, privileged information and confidentiality.

  • Week 3: Scientific Record Keeping and Data Management

    Week 3:        

    Wednesday, April 22 (Health Sciences West 300) or Thursday, April 23 (Byers Aud., Genentech Hall 106)

     

    Scientific Record Keeping and Data Management

    Xiaokun Shu – Assistant Professor, Pharmaceutical Chemistry

    Accepted practices for acquiring and maintaining research data. Proper methods for record keeping and electronic data collection and storage in scientific research. Includes defining what constitutes data; keeping data notebooks or electronic files; data privacy and confidentiality; data selection, retention, sharing, ownership, and analysis; data as legal documents and intellectual property, including copyright laws.

  • Week 4: The Art of Mentorship and Being Mentored

    Week 4:        

    Wednesday, April 29 (Health Sciences West 300) or Thursday, April 30 (Byers Aud., Genentech Hall 106)

     

    The Art of Mentorship and Being Mentored

    Keith Yamamoto – Professor, Cellular and Molecular Pharm.; Executive Vice Dean for Research, UCSF School of Medicine; and Vice Chancellor for Research

    The responsibilities of mentors and trainees in predoctoral and postdoctoral research programs. Includes the role of a mentor, responsibilities of a mentor, conflicts between mentor and trainee, collaboration and competition, selection of a mentor, abuse of the mentor/trainee relationship, and policies for handling misconduct.

  • Week 5: Science Outside of the Academy - Conflicts of Interest

    Week 5:        

    Wednesday, May 6 (Cole Hall) or Thursday, May 7 (Byers Aud., Genentech Hall 106)

     

    Science Outside of the Academy - Conflicts of Interest

    Karin Immergluck -- Director of Technology Mgmt, Office of Innovation, Technologies and Alliances (ITA)

    Tom Lang – Chair of the UCSF Chancellor’s Conflict of Interest Advisory Committee; Professor, UCSF School of Medicine

    The definition of conflicts of interest and how to handle conflicts of interest. Types of conflicts encountered by researchers and institutions. Includes topics such as conflicts associated with collaborators, publication, financial conflicts, obligations to other constituencies, and other types of conflicts.

  • Week 6: Science in the Genomic Era: Biomedical Research and Human Subjects

    Week 6:        

    Wednesday, May 13 (Health Sciences West 300) or Thursday, May 14 (Byers Aud., Genentech Hall 106)

     

    Science in the Genomic Era: Biomedical Research and Human Subjects

    Ulluminair Salim – Director, Responsible Conduct of Research for Postdoctoral Scholars

    Kevin Shannon – Auerback Distinguished Professor, Pediatric Molecular Oncology

    Zena Werb – Professor and Vice-Chair, Anatomy

    Issues pertaining to biomedical research and human subjects protections in the genomic era: privacy, confidentiality and protection of human tissue donors; management of genomic data; informed and open consent; and ethical issues in genomics research with vulnerable populations.

  • Week 7: Animal Welfare in Research

    Week 7:        

    Wednesday, May 20 (Health Sciences West 300) or Thursday, May 21 (Byers Aud., Genentech Hall 106)

     

    Animal Welfare in Research                     

    Jessica Couch—Senior Scientist and Safety Assessment Therapeutic Area Lead for Biotherapeutic Neuroscience, Genentech

    Issues important in the use of animals in conducting research. Includes topics such as definition of research involving animals, ethical principles for conducting research on animals, federal regulations governing animal research, institutional animal care and use committees, and treatment of animals.

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