Section outline

  • General

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  • Tuesday, September 16, 2014; 8:45 AM - 10:15 AM

    Lecture: Course Introduction; Study Design
    Distinction between designs where the unit of observation is a group of individuals vs. the individual; ecological fallacy; types of studies with observations on the individual; cohort study as gold standard of observational designs; concept of study base linking cohort and case-control designs.

    Faculty:  Jeffrey Martin and Ann Schwartz

    Location:  China Basin 6702

    • Prospectus:

    • Introductory Comments 2014 File
    • Introductory Comments (Mediasite version) URL
    • Introductory Comments (.mp4 version) URL

    • Session Slides:

    • Study Design 2014 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    •  S & N: Ch. 1, p. 3 – 32.
    • Wachholder, S. Selection of controls in case-control studies. Am J Epidemiol 135:1019 – 1028, 1992. Focus on “Study Base Principle” p. 1021 - 1024. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Vandenbroucke JP. Prospective vs retrospective: What's in a name? BMJ 302: 249-250, 1991 File
      Not available unless: Your ID number contains 02
    • Vandenbroucke JP and Pearce N. Case control studies: Basic Concepts. International Journal of Epidemiology 41: 1480-1489, 2012 File
      Not available unless: Your ID number contains 02

    • Assignment:  Problem Set 1

    • Problem Set 1 Study Design 2014 File

    • Assignment Due Date:  September 23, 2014 at the beginning of Small Group Section

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, September 23, 2014; 8:45 AM - 10:15 AM

    Lecture: Measures of Disease Occurrence I

    Prevalence vs. incidence; the three elements in measuring disease incidence; the concept of a rate; cumulative incidence vs. person-time incidence; concepts of survival analysis—failure time and censoring; calculating cumulative incidence—Kaplan Meier and life table methods.

    Faculty:  Ann Schwartz

    Location:  China Basin 6702

    • Prospectus:

    • Announcements Week 2 File

    • Session Slides:

    • Disease Occurrence I 2014 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    •   S & N: Ch. 2

    • Tapia Granados, JA. On the terminology and dimensions of incidence. J Clin Epidemiol 50:891 – 897, 1997. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Kaplan EL and Meier P. Nonparametric estimation from incomplete observations. J. American Stat. Assoc. 282: 457-481, 1958 File
      Not available unless: Your ID number contains 02
    • Rothman K. Measuring disease occurrence and causal effects. In Epidemiology: An Introduction. Oxford University Press. 38 - 56, 2012. File
      Not available unless: Your ID number contains 02
    • Rich JT et al. A practical guide to understanding Kaplan-Meier curves. Otolaryngol. Head Neck Surg. 143:331-336, 2010. File
      Not available unless: Your ID number contains 02

    • Assignment:  Problem Set 2

    • Problem Set 2 Disease Occurrence I 2014 [WORD Verson] File
    • Problem Set 2 Disease Occurrence I 2014 [PDF Version] File
    • Epi203survival File
    • Summary of basic Stata survival analysis commands File

    • Assignment Due Date:  September 30, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, September 23, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley CB6702, Aiemjoy CB 6601, Ray CB 5759, Wang CB 5721, Semeere Online

     

  • Tuesday, September 30, 2014; 8:45 AM - 10:15 AM

    Lecture: Measures of Disease Occurrence II
    Person-time incidence rates; rate is not a proportion; instantaneous rate; person-time based on grouped data vs. individual data; assumption that unit of person-time in denominator does not matter; stratified person-time exposure in cohort studies; relationship of prevalence to incidence; competing events.

    Faculty:  Ann Schwartz

    Location:  China Basin 6702

    • Session Slides:

    • Disease Occurrence II 2014 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    •   S & N: Ch. 2

    • Satagopan et al. A note on competing risks in survival data analysis. Brit J Cancer 91:1229-1235, 2004. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Vandenbroucke JP and Pearce N. Incidence rates in dynamic populations IJE 41: 1472-1479, 2012. File
      Not available unless: Your ID number contains 02
    • Tager, IB. Outcomes in cohort studies. Epidemiol Rev 20:15-28, 1998. File
      Not available unless: Your ID number contains 02
    • Grunkemeier et al. Actual and actuarial probabilities of competing risks: Apples and lemons. Ann Thoracic Surg 83:1586-1592, 2007. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 3

    • Problem Set 3 Disease Occurrence II 2014 File

    • Assignment Due Date: October 7, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, September 30, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley CB6702, Aiemjoy CB 6601, Ray CB 5759, Wang CB 5721, Semeere Online

     

  • Tuesday, September 30, 2014; 3:15 PM - 4:15 PM (Times and dates for online sessions may differ)

    Journal Club

    Application of concepts learned in the course to date in the critical dissection of an article in the applied literature

    Faculty:  Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location:  Students will stay in the rooms of their prior small group sections. Semeere online.

    • Required Reading:

    • Ondrusova and Ondrus. Epidemiology and treatment delay in testicular cancer patients: a retrospective study. Int Urol Nephrol 40:143-148, 2008 File
      Not available unless: Your ID number contains 02
    • Journal Club Guide to Reviewing an Article File

    • Assignment Answer Key (Access restricted to registered students):

    • Journal Club 1 KEY File
      Not available unless: Your ID number contains 02

  • Tuesday, October 7, 2014; 8:45 AM - 10:15 AM (Times and dates for online sessions may differ)

    Lecture: Measures of Disease Association I

    Measures of association in cross-sectional and cohort studies; 2 x  2 tables; prevalence ratio and prevalence odds ratio; advantages and disadvantages of odds ratios; risk, rate, and hazard ratios; difference vs ratio measures; describing measures of association

    Faculty:  Ann Schwartz

    Location:  China Basin 6702

    • Session Slides:

    • Disease Association I 2014 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    •   S & N: Ch. 3, except sections 3.2.2 and 3.4.2 (i.e., skip attributable risk); Appendix A3 (P. 435 - 438)

    • Schulman et al. The effect of race and sex on physician's recommendations for cardiac catheterization. NEJM 340:618 – 626, 1999. File
      Not available unless: Your ID number contains 02
    • Schwartz et al. Misunderstandings about the effects of race and sex on physicians' referrals for cardiac catheterization. NEJM 341:279 – 283, 1999. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Cummings P. The relative merits of risk ratios and odds ratios. Arch Pediatr Adolesc Med. 163:438-445, 2009. File
      Not available unless: Your ID number contains 02
    • Holcomb et al. An odd measure of risk: use and misuse of the odds ratio. Obstet Gynecol 98:685-688, 2001. File
      Not available unless: Your ID number contains 02
    • Cummings P. Methods for estimating adjusted risk ratios. The Stata Journal 9:175-196, 2009. File
      Not available unless: Your ID number contains 02
    • Poole C. On the origin of risk relativism. Epidemiology 21:3-9, 2010. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 4

    • Problem Set 4 Disease Association 2014 File

    • Assignment Due Date:  October 14, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, October 7, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley CB6702, Aiemjoy CB 6601, Ray CB 5759, Wang CB 5721, Semeere Online

     

  • Tuesday, October 14, 2014; 8:45 AM - 10:15 AM

    Lecture: Measures of Disease Association II and Measures of Attribution

    Measures of association in a case-control study; equivalence of odds ratio to other measures of association depending on control sampling: case-cohort, incidence density, or prevalent; measures of attribution: attribution among exposed vs attribution in an overall population.

    Faculty:  Ann Schwartz

    Location:  China Basin 6702

    • Prospectus:

    • Announcements Week 5 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Session Slides:

    • Disease Association II and Attribution 2014 File

    • Required Reading:

    • S & N: Ch. 3, including sections 3.2.2 and 3.4.2; Appendix A4 and A5 (p. 438 - 442)

    • Optional Reading:

    • Greenland S and Robins JM. Conceptual problems in the definition and interpretation of attributable fractions. American Journal of Epidemiology 128:1185-1197, 1988. File
      Not available unless: Your ID number contains 02
    • Rockhill B, Newman B, and Weinberg C. Use and misuse of population attributable fractions. American Journal of Public Health 88:15-19, 1998. File
      Not available unless: Your ID number contains 02
    • Rundle AG, Vineis P, and Ahsan H. Design options for molecular epidemiology research within cohort studies. Cancer Epidemiol Biomarkers Prev. 14:1899-907, 2005. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 5

    • Problem Set 5 Disease Association II 2014 File
    • fracturegenotype File

    • Assignment Due Date:  October 21, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, October 14, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley CB6702, Aiemjoy CB 6601, Ray CB 5759, Wang CB 5721, Semeere Online

     

  • Tuesday, October 14, 2014; 3:15 PM - 4:15 PM (Times and dates for online sessions may differ)

    Journal Club

    Application of concepts learned in the course to date in the critical dissection of an article in the applied literature

    Faculty:  Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location:  Students will stay in the rooms of their prior small group sections. Semeere Online.

    • Required Reading:

    • Grosso et al. Oral Bisphosphonates and Risk of Atrial Fibrillation and Flutter in Women: A Self-Controlled Case-Series Safety Analysis. PLoS ONE 4:e4720, 2009 File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, October 21, 2014; 8:45 AM - 10:15 AM

    Lecture: Selection Bias

    Internal vs. external validity; definition and classification of bias; distinguishing bias from random error; spotting and minimizing selection bias in descriptive, cross-sectional, case-control, and longitudinal (e.g., cohorts or trials) studies

    Faculty:  Jeffrey Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • Selection Bias 2014 Final Post File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • S & N:  Ch. 4, sections 4.1 - 4.2 (p. 109 - 116) and sections 4.4 - 4.4.2 (p. 133 - 139)

    • Optional Reading:

    • Hernán MA, Hernández-Díaz S, Robins JM. A structural approach to selection bias. Epidemiology. 15:615-25, 2004. File
      Not available unless: Your ID number contains 02
    • Robinson et al. Systematic review identifies number of stategies important for retaining study participants. J Clin Epi 60:757-765, 2007. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 6

    • Assignment Due Date:  October 28, 3014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, October 21, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH 2105, Aiemjoy MH 2106, Ray MH 2107, Wang MH 2108, Semeere Online

     

  • Tuesday, October 28 2014; 8:45 AM - 10:15 AM

    Lecture: Understanding Measurement: Aspects of Reproducibility and Validity

    Distinguishing reproducibility from validity; how reproducibility influences validity; methods of characterizing reproducibility of measurements (within-subject standard deviation, intraclass correlation coefficient,  coefficient of variation); methods of assessment of validity in the presence and absence of gold standards

    Faculty:  Jeffrey Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • Measurement Reproducibility Validity 2014 Final Post File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch (Mediasite version) URL

    • Required Reading:

    • S & N: Chapter 8 : Sections 8.1 - 8.2 (p. 313 - 315), sections 8.3.1 - 8.3.3 (p. 318 - 328), and section 8.4.2 (p. 348 - 358)

    • Bland and Altman. Measurement error proportional to the mean. BMJ 313:106, 1996. File
      Not available unless: Your ID number contains 02
    • Bland and Altman. Measurement error and correlation coefficients. BMJ 313:41-42, 1996 File
      Not available unless: Your ID number contains 02
    • Bland and Altman. Measurement error. BMJ 313:744, 1996. File
      Not available unless: Your ID number contains 02
    • Mc Dowell and Newell. Measuring Health: A guide to rating scales and questionnaires. Oxford 29-37, 1996. File
      Not available unless: Your ID number contains 02
    • Bland and Altman. Applying the right statistics: analyses of measurement studies. Ultrasound Obstet Gynecol 22: 85-93, 2003. File
      Not available unless: Your ID number contains 02
    • Bland and Altman. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 307-310, 1986. File
      Not available unless: Your ID number contains 02
    • Measurement Summary Chart File

    • Optional Reading:

    • Weir, JP. Quantifying test-retest reliability using the intraclass correlation coefficient and the SEM. JSCR 19:231-240, 2005. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 7

    • Assignment Due Date:  November 4, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, October 28, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH-2105, Aiemjoy MH-2106, Ray MH-2107, Wang MH-2108, Semeere Online

     

  • Tuesday, October 28, 2014; 3:15 PM - 4:15 PM (Times and dates for online sessions may differ)

    Journal Club

    Application of concepts learned in the course to date in the critical dissection of an article in the applied literature

    Faculty:  Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location:  Students will stay in the rooms of their prior small group sections. Semeere (online)

    • Required Reading:

    • Lane et al. Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women. Arthritis and Rheumatism 56:3319–3325, 2007. File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (Access restricted to registered students):

    • Journal Club 3 2014 Discussion Key File
      Not available unless: Your ID number contains 02

  • Tuesday, November 4, 2014; 8:45 AM - 10:15 AM

    Lecture: Measurement Bias
    Differential vs non-differential misclassification; independent vs dependent errors;  influence (magnitude and direction of bias) of differential vs. non-differential and independent vs dependent misclassification of exposure, outcome, and confounding variables

    Faculty:  Jeffrey Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • Measurement Bias 2014 Final Post File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • S & N:  Ch. 4: sections 4.3-4.3.3 (P. 116-133)

    • Optional Reading:

    • Shahar, E. Causal diagrams for encoding and evaluation of information bias. Journal of Evaluation in Clinical Practice 15: 436-440, 2009. File
      Not available unless: Your ID number contains 02
    • Jurek, AM et al. Proper interpretation of non-differential misclassification effects. J Epid 34:680-687, 2005. File
      Not available unless: Your ID number contains 02
    • Berry et al. Impact of misclassification of in vitro fertilization in studies of folic acid and twinning: modelling using population based Swedish vital records. BMJ 1-3, 2004. File
      Not available unless: Your ID number contains 02
    • Hernan and Cole. Causal diagrams and measurement bias. AJE 170:959-962, 2009. File
      Not available unless: Your ID number contains 02
    • Kristensen P. Bias from nondifferential but dependent misclassification of exposure and outcome. Epidemiology 3:210-215, 1992. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 8

    • Problem Set 8 Measurement Bias 2014 File

    • Assignment Due Date:  November 18, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, November 4, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH-2105, Aiemjoy MH-2106, Ray MH-2107, Wang MH-2108, Semeere Online

  • Tuesday, November 11, 2014

    No Class - Veterans Day Holiday

  • Tuesday, November 18, 2014; 8:45 AM - 10:15 AM

    Lecture: Confounding and Interaction I: General Principles

    Definition and manifestations of confounding; requirements for confounding variables; use of directed acyclic graphs (DAGs) to demonstrate and identify confounding; extraneous causal pathways; importance of defining the research question and the biological system to prevent confounding

    Faculty:  Jeffrey Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • Confounding I 2014 Final Post File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch (.MP4) URL

    • Required Reading:

    •   S & N: Ch. 5

    • Jewell, NP. Causal inference and extraneous factors: confounding and interaction. In Statistics for Epidemiology. Chapman and Hall. p. 93-112, 2003. File
      Not available unless: Your ID number contains 02
    • DAGitty dot net instructions File
    • Notes on reading for Confounding and Interaction I File

    • Optional Reading:

    • Hernan M. Causal knowledge. AJE 156:176-184, 2002. File
      Not available unless: Your ID number contains 02
    • Cole S, Hernan M. Fallibility in estimating direct effects. IJE 31:163-165, 2002. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 9

    • Problem Set 9 Confounding and Interaction I 2014 File

    • Assignment Due Date:  November 25, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, November 18, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH-2105, Aiemjoy MH-2106, Ray MH-2107, Wang MH-2108, Semeere Online

  • Tuesday, November 18 2014; 3:15 PM - 4:15 PM (Times and dates for online sessions may differ)

    Journal Club

    Application of concepts learned in the course to date in the critical dissection of an article in the applied literature

    Faculty:  Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location:  Students will stay in the rooms of their prior small group sections. Semeere (Online)

    • Required Reading:

    • Rookus M and van Leeuwen FE. Induced abortion and risk for breast cancer. Reporting (recall) bias in a Dutch case-control stduy. Journal of the National Cancer Institute 88:1759-1764, 1996. File
      Not available unless: Your ID number contains 02

    • Assignment Answer Key (Access restricted to registered students):

    • Journal Club 4 Rookus et al JNCI Discussion Guide File
      Not available unless: Your ID number contains 02

  • Tuesday, November 25, 2014; 8:45 AM - 10:15 AM (Times and dates for online sessions may differ)

    Lecture: Confounding and Interaction II: Concepts of Interaction

    Strategies to minimize confounding; types of interaction; distinguishing interaction from confounding; assessing for interaction; tests of homogeneity; computer implementation

    Faculty:  Jeffrey Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • Confounding and Interaction II 2014 Final Post File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • S & N: Ch. 6 and Ch. 1, section 1.4.5 (p. 33 - 38, section on Matching)

      dagitty.net, an open source browser-based environment for creating, editing, and analyzing directed acyclic graphs

    • Optional Reading:

    • VanderWeele TJ and Robins JM. Four types of effect modification: A classification based on directed acyclic graphs. Epidemiology 18: 561-568, 2007. File
      Not available unless: Your ID number contains 02
    • Knol MJ et al. When one depends on the other: Reporting of interaction. Epidemiology 20:161-166, 2009. File
      Not available unless: Your ID number contains 02
    • Knol MJ and VanderWeele TJ. Recommendations for presenting analyses of effect modification and interaction. International Journal of Epidemiology 41:514-520, 2012. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 10

    • Problem Set 10 Confounding and Interaction II 2014 File

    • Assignment Due Date:  December 2, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, November 25, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section

    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH-2105, Aiemjoy MH-2106, Ray MH-2107, Wang MH-2108, Semeere Online

  • Tuesday, December 2, 2014; 8:45 AM - 10:15 AM

    Lecture: Confounding and Interaction III: Stratified Analysis

    Concept of weighted averages; use of stratification to form adjusted measures; managing multiple confounding paths; software implementation to detect minimally sufficient set for adjustment; limitations of stratification including time-dependent confounding/mediation

    Faculty:  Jeffrey Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • Confounding and Interaction III 2014 Final Post File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

      S & N: Ch. 7: sections 7.1 - 7.2.1 (p. 229 - 234) and sections 7.3.3 - 7.3.4 (p. 242 - 248)

      dagitty.net, an open source browser-based environment for creating, editing, and analyzing directed acyclic graphs

    • Optional Reading:

    • Shrier I and Platt W. Reducing bias through directed acyclic graphs. BMC Medical Research Methodology, 8:70, 2008. File
      Not available unless: Your ID number contains 02
    • Suarez et al. Differences between marginal structural models and conventional models in their exposure effect estimates. Epidemiology 22: 586-588, 2011. File
      Not available unless: Your ID number contains 02

    • Assignment: Problem Set 11

    • Problem Set 11 Confounding and Interaction III 2014 File
    • esophageal cancer File

    • Assignment Due Date:  December 9, 2014

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, December 2, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH-2105, Aiemjoy MH-2106, Ray MH-2107, Wang MH-2108, Semeere Online

  • Tuesday, December 2, 2014; 3:15 PM - 4:15 PM (Times and dates for online sessions may differ)

    Journal Club

    Application of concepts learned in the course to date in the critical dissection of an article in the applied literature

    Faculty:  Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location:      Students will stay in the rooms of their prior small group sections. Semeere Online

    • Required Reading:

    • Nitz et al. Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations. Journal of Clinical Endocrinology & Metabolism 92:3183–3188, 2007. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Lunnetta KL. Genetic association studies. Circulation 118:96-101, 2008. File
      Not available unless: Your ID number contains 02
    • Glossary for Nitz et al. File

    • Assignment Answer Key (Access restricted to registered students):

    • Journal Club 5 Nitz Discussion KEY 2014 File
      Not available unless: Your ID number contains 02

  • Tuesday, December 9, 2014; 8:45 AM - 10:15 AM (Times and dates for online sessions may differ)

    Journal Club

    Application of concepts learned in the course to date in the critical dissection of an article in the applied literature

    Faculty:  Jeff Martin

    Location:  Mission Hall 1400

    • Session Slides:

    • MMR and Autism NEJM 2002 2014 Final Post File
    • Course Finale Comments 2014 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Madsen et al., A population-based study of measles, mumps, and rubella vaccination and autism. NEJM 347:1477-82, 2002. File
      Not available unless: Your ID number contains 02

    • Optional Reading:

    • Writing a Manuscript Template File
    • von Elm et al. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: Guidelines for reporting observational studies. Lancet 370:1453-1457, 2007. File
      Not available unless: Your ID number contains 02
    • Vandenbroucke et al. Strengthening the reporting of observational studies in epidemiology (STROBE): Explanation and elaboration. PLoS Medicine 4:e297, 2007. File
      Not available unless: Your ID number contains 02

    • Assignment: Final Exam

    • Yaggi et al. Obstructive sleep apnea as a risk factor for stroke and death. NEJM 353:2034-41. 2005. File
      Not available unless: Your ID number contains 02
    • brcarctv6 File

    • Assignment Due Date:  Final Exam due December 16, 2014 by  4 pm for inclass students and December 17, 2014 by 9 pm for online students.

      • You must log into the CLE to upload your assignment.
      • Please upload as a .pdf such that all your formatting will be preserved.
    • Upload EPI 203 Final Exam here. Assignment

  • Tuesday, December 9, 2014; 1:30 PM - 3:00 PM (Times and dates for online sessions may differ)

    Small Group Discussion Section
    Review of prior lecture and problem set

    Faculty: Sarah Ackley, Kristen Aiemjoy, Kathryn Ray, Ralph Wang, Elvin Geng, Trisha Hue, Jeff Martin, Ann Schwartz, Aggrey Semeere

    Location: Ackley MH-2105, Aiemjoy MH-2106, Ray MH-2107, Wang MH-2108, Semeere Online