Section outline

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  • Thursday, March 31, 2016; 1:00 PM - 2:30 PM

    Lecture: Designing a Systematic Review
    Indications and overview of the steps of systematic reviews, how to formulate research questions and developing a protocol, Data sources, search strategy and publication bias; inclusion and exclusion criteria, quality assessment, data abstraction forms, selection of studies, homogeneity.

    Faculty:  Steve Bent
     
    Location:  Mission Hall 1400

    • Prospectus:

    • Session Slides:

    • SR lecture March 31 2016 File
    • Lecture 1.2016 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL

    • Required Reading:

    • Bent - AJIC - Systematic Reviews File
      Not available unless: Your ID number contains 02

    • Optional Reading:

      Systematic Reviews in Health Care, chapters 2,3,4 & 5

    • Moher D, Liberati A , Tetzlaff J, Altman DG. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. File
      Not available unless: Your ID number contains 02
    • Jadad AR et al. Assessing the Quality of Reports of Randomized Controlled Clinical Trials: Is Blinding Necessary? Controlled Clinical Trials. 1996;17:1-12. File
      Not available unless: Your ID number contains 02
    • Hayden JA et al. Evaluation of the quality of prognostic studies in systematic reviews. Annals of Internal Medicine. 2006;144:427-437. File
      Not available unless: Your ID number contains 02

  • Thursday, April 7, 2016; 1:00 PM - 2:30 PM

    Section 1: (Divided section)

    Part A: 50 min: Developing a Protocol for Systematic Review with Ashok Krishnaswami

    Part B: 30 min:  Literature Search with Min-Ling Fan

    Faculty: Elaine Allen, Dejana Braithwaite, Ashok Krishnaswami (Part A)\Min-Ling Fan (Part B)

    Location:  MH 1400

    • Session Slides:

    • Literature Searching for SR-4-2016-2 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL

    • Required Reading:

    • Articles A, B, C, D File
      Not available unless: Your ID number contains 02

    • Assignment:

    • Section 1.2016 File

  • Thursday, April 14, 2016; 1:00 PM - 2:30 PM

    Lecture:  Analytical Methods
    Fixed and random effects models, summary estimates of effect and variance, subgroup and sensitivity analysis, statistical approaches to publication bias, presenting results of meta-analysis.

    Faculty:  I. Elaine Allen

    Location:  Mission Hall 1400

    • Session Slides:

    • Lecture 2 2016 File
    • Methods-4-14-2016new File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch URL

    • Required Reading:

    • meta.analysis File
      Not available unless: Your ID number contains 02
    • Prospero BreastCancer File
      Not available unless: Your ID number contains 02
    • SystematicReviews10-2015 File
      Not available unless: Your ID number contains 02
    • kovalchik meta tutorial File
      Not available unless: Your ID number contains 02
    • meerwijk 2016b onlinefirst File
      Not available unless: Your ID number contains 02
    • Neurology-2016-Feldman File
      Not available unless: Your ID number contains 02

    • Optional Reading:

      Egger M, Davey Smith G, Altman D. Systematic reviews in health care: Meta-analysis in context. Chapters 15-17.

    • Egger M, Ebrahim S, Smith GD. Where now for meta-analysis? International Journal of Epidemiology. 2002;31:1-5. File
      Not available unless: Your ID number contains 02
    • Shrier I, Platt RW, Steele RJ. Mega-trials vs. meta-analysis: Precision vs. heterogeneity? Contemporary Clinical Trials. 2007;28:324–328 File
      Not available unless: Your ID number contains 02
    • Moher D, Schulz KF, Altman DG. The CONSORT Statement: Revised Recommendations for Improving the Quality of Reports of Parallel-Group Randomized Trials. Annals of Internal Medicine. 2001;134:657-62. File
      Not available unless: Your ID number contains 02
    • Juni - Hazards of quality scoring File
      Not available unless: Your ID number contains 02
    • SR - meta-analysis vs mega-trials File
      Not available unless: Your ID number contains 02

  • Thursday, April 21, 2016; 1:00 PM - 2:30 PM

    Section: Performing a Meta-analysis

    Faculty:  Steve Bent

    Location: Mission Hall 1400

    • Prospectus:

    • Section 2 2016 File

    • Session Slides:

    • Systematic Review MA HW2 PPT File
    • WWTBM - EBM File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Optional Reading:

    • Assignment:  Complete Section 2 Problem Set

    • Datasets:

    • hw02-2 File
    • hw02-1 File

  • Thursday, April 28, 2016; 1:00 PM - 2:30 PM

    Lecture: Advanced techniques in meta-analysis

    Faculty: I. Elaine Allen

    Location:      Mission Hall 1400

    • Prospectus:

    • Lecture 3 2016 File

    • Session Slides:

    • AdvancedTechniques4-28-2016 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Optional Reading:

      Egger M, Davey Smith G, Altman D. Systematic reviews in health care: Meta-analysis in context. Chapters 15-16

      Leeflang MMG, Deeks JJ, Gatsonis C, Bossuyt PMM. Systematic reviews of diagnostic test accuracy. Ann Int Med. 2008;149:889-897.

    • Resources:

    • Appendix S1-StataCommands File

    • Final Exam: 

    • SR EXAM 2016 File

    • Final Exam Due Date: May 12, 2016 at 5:00pm

      Please submit this exam electronically by e-mailing to systematicreviews2016@gmail.com

  • Thursday, May 5, 2016; 1:00 PM - 2:30 PM

    Journal Club

    Faculty:  Steve Bent

    Location: MH 1400

    • Session Slides:

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:

    • Alter HJ et al. Intravenous magnesium as an adjuvant in acute bronchospasm: a meta-anlaysis. Annals of Emergency Medicine. 2000;36:191-197. File
      Not available unless: Your ID number contains 02
    • Rowe BH et al. Intravenous magnesium sulfate treatment for acute asthma in the emergency department: a systematic review of the literature. Annals of Emergency Medicine. 2000;36:181-190. File
      Not available unless: Your ID number contains 02

    • Assignment:  Section 3 Homework: 1-2 page critique of the following systematic reviews:

    • Section 3 2015 File

    • Final Exam: 

    • Final Exam: to be posted April 28, 2016.  Complete and e-mail by May 12, 5pm to: systematicreviews2016@gmail.com