Section outline

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  • Tuesday, January 5, 2021; 1:30 PM - 3:00 PM

    Lecture: Introduction, the Big Picture

    The process of genetic epidemiology; general approaches to assess the genetic basis of disease.

    Faculty:  John Witte

    Zoom: https://tinyurl.com/ybec6nu4

    • Session Slides:

    • Lecture 1 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Watch 2021 Media Resource

    • Required Reading:

      Relevant journal articles will be assigned throughout the quarter. These should be read before the corresponding class meeting. Students will contribute to discussion of journal articles.

    • Genetic Epi chapter File
    • AHA Reading File

    • Assignment:

    • Assignment 1

    • Final Exam: Optional narrative description

    • Final project File

    • Written Final Project Due Date: Due on 3/12 by email to all of Yusuph Mavura (yusuph.mavura@ucsf.edu) Thomas Hoffmann (hoffmannt@humgen.ucsf.edu) and John Witte (John.Witte@ucsf.edu)

      Also, Brief Presentation of Project in the Final Class on 3/16

  • Tuesday, January 12, 2021; 1:30 PM - 3:00 PM

    Lecture: Population Genetics, Heritability, Familiality 

    Faculty:  John Witte

    Location (Access restricted to registered students): Zoom URL

    • Session Slides:

    • Lecture 2 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 2 Media Resource

    • Required Reading:

    • Visscher File

    • Assignment:

    • Assignment 2

    • Assignment Answer Key (Access restricted to registered students):

    • Assignment 2 key File

  • Tuesday, January 19, 2021; 1:30 PM - 3:00 PM

    Lecture: Association Studies

    Faculty:  John Witte

    Location: Zoom

    • Session Slides:

    • Lecture3-Intro to Association File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture3 Media Resource

    • Required Reading:


    • History of Human Genetics File

    • Assignment:

    • Assignment 3

    • Assignment Answer Key (Access restricted to registered students):

    • assignment key3 File

  • Tuesday, January 26, 2021; 1:30 PM - 3:00 PM

    Lecture: Genome-wide Association Studies (GWAS)

    Introduction to genome-wide association studies (GWAS): study design, array design, and initial analysis

    Faculty:  Thomas Hoffmann

    Location (Access restricted to registered students): Zoom URL

  • Tuesday, February 2, 2021; 1:30 PM - 3:00 PM

    Lecture: GWAS (Part II)

    Imputation, etc.

    Faculty:  Thomas Hoffmann

    Location (Access restricted to registered students): Zoom URL

    • Session Slides:

    • Lecture5 GWAS File
    • Lecture5 GWAS File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 5 Media Resource

    • Assignment:

    • Assignment 5 File
    • Assignment 5

    • Assignment Answer Key (Access restricted to registered students):

    • Assignment5 key File

  • Tuesday, February 9, 2021; 1:30 PM - 3:00 PM

    Lecture: GWAS (Part III)

    Faculty: Tom Hoffmann

    Location (Access restricted to registered students): Zoom URL

    • Session Slides:

    • Lecture6 GWAS File
    • Lecture6 GWAS File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture 6 Media Resource

    • Assignment: Optional narrative description

    • Assignment 6

    • Assignment Answer Key (Access restricted to registered students):

    • Assignment 6 key 2021 File

  • Tuesday, February 16, 2021; 1:30 PM - 3:00 PM

    Lecture: Polygenic Risk Scores / Mendelian Randomization

    Faculty: Linda Kachuri

    Location: Zoom

    • Session Slides:

    • Genetic Epidemiology - PRS MR File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Lecture7_PRS Media Resource

    • Required Reading:

    • Assignment: Optional narrative description

    • Assignment 7

    • Assignment Answer Key (Access restricted to registered students):

    • Week 7 key File

  • Tuesday, February 23, 2021; 1:30 PM - 3:00 PM

    Lecture: Genetic Epidemiology in Diverse Populations

    Faculty:  Taylor Cavazos

    Location: Zoom https://tinyurl.com/ybec6nu4


    • Session Slides:

    • Week 8 epid217 File

    • Session Audio/Video Recording (Access restricted to registered students):

    • Week 8 lecture Media Resource

    • Assignment:

    • Assignment 8

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, March 2, 2021; 1:30 PM - 3:00 PM

    Lecture: Gene-Environment Interactions, Microbiome 

    Faculty:  Iona Cheng

    Location: Zoom  https://tinyurl.com/ybec6nu4

    • Session Slides:

    • GXE Gut Microbiome 3-2-2021 File

    • Session Audio/Video Recording:

    • Lecture 9 Media Resource
    • Bonder et al. 2016 File

    • Final Exam: Optional narrative description

    • Written Final Project Due Date: Due on 3/12 by email to all of Yusuph Mavura (yusuph.mavura@ucsf.edu) Thomas Hoffmann (hoffmannt@humgen.ucsf.edu) and John Witte (John.Witte@ucsf.edu)

      Also, Brief Presentation of Project in the Final Class on 3/16

    • Assignment: Optional narrative description

    • Assignment 9
    • Assignment 9 key File

  • Tuesday, March 9, 2021; 1:30 PM - 3:00 PM

    Lecture: Viral Genomics

    Faculty:  Stephen Francis

    Location: Zoom  https://tinyurl.com/ybec6nu4

    • Session Slides:

    • Gen Epi ViralMeta 2021 share File
    • Week 10 Media Resource

    • Required Reading:

    • Assignment: Optional narrative description

    • Assignment Answer Key (Access restricted to registered students):

  • Tuesday, March 16, 2021; 1:30 PM - 3:00 PM

    Lecture: Putting it all Together: Incorporating Molecular and Genetic Measures into Your Research

    Final Project Presentations.

    Faculty:  John Witte, Tom Hoffmann

    Location:     Zoom https://tinyurl.com/ybec6nu4

    • Session Audio/Video Recording (Access restricted to registered students):

    • Required Reading:


    • Assignment: Optional narrative description

    • Assignment Answer Key (Access restricted to registered students):