EPI 222: Social Determinants of Health and Health Disparities: What Every Researcher Should Know (Winter 2021)
Section outline
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Jack Talyor Forum
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Michelle Lee Forum
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Safyer McKenzie-Sampson Forum
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Lecture: Introduction to research with diverse populations
Research in diverse populations requires an understanding of the complex multi-level influences on human health and how these are patterned by sociodemographic characteristics, including race/ethnicity and socioeconomic status. This lecture will provide an introduction to conceptual models for these multi-level influences on health and their relevance to research of all types on human health. This multi-level framework will then provide the structure for the following three lectures of the course, which will review sequential layers of this model.
Faculty: Christine Dehlendorf
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Watch - Live lecture Media Resource
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Levels of Racism: A Theoretic Framework and a Gardener’s Tale, Camara Phyllis Jones, MD, MPH, PhD File
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Robert Wood Johnson Foundation - Overcoming Obstacles to Health- Chapter 1 File
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Paradigms of Epidemiology File
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Homework Help
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Lecture: Multi-level etiologies of health in diverse population, Part 1: Social determinants of health and health behaviors
Social determinants of health are the conditions in which people are born, grow, work, live, and age, including education, wealth, occupation, neighborhood of residence, and the experience of racism. These factors are increasingly recognized as critical upstream influences that drive individual level health, as well as differences in health across groups. This lecture will provide an overview of what is known about the role of social determinants and about their influence on health behaviors and health itself.
Faculty: Salma Shariff-Marco and Scarlett Gomez
Location (Access restricted to registered students): Zoom URL-
Watch - Live Lecture Media Resource
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Lecture - Please review before Jan. 12 Media Resource
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Robert Wood Johnson Foundation - Overcoming Obstacles to Health- Chapter 3 File
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Freeman CRT File
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DM Christine File
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Pampel Annu Review File
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DM Steve File
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Thakur SDOH COVID ATS Journals 2020 File
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Lecture: Multi-level etiologies of health in diverse populations, Part 2: Health systems and health care determinants
While the social determinants of health are key in determining who gets sick, health care access and quality is key to determining the outcome of illness. This class will review how ethnic/racial (and other) health care disparities play out in the highly complex US health care system. We will discuss the contributions of provider bias, health system structural inequities, and segregated care to health care disparities while also examining how fundamental assumptions about the role of the individual, family, and society play out in the care of acute and chronic illness. Finally, we will review the experience of quality improvement programs in mitigating health care disparities.
Faculty: Christine Dehlendorf and Cassondra Marshall
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Watch -Live Lecture Media Resource
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Lecture - Please review before Jan. 19 Media Resource
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Hidden Curriculum Brooks File
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chapman Bias File
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LEP DM File
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pnas.201516047 pain article File
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iom on health disparities.020601 File
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5. Sacks - Race and Gender Concordance File
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Infant Mortality File
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Dovidio 2008 File
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implicitbias review File
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Homework Help
Location (Access restricted to registered students): Zoom URL
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Lecture: Multi-level etiologies of health in diverse populations, Part 3: Biological determinants, mediators and mechanisms
One of the most active areas of health disparities research is understanding how social experiences get “under the skin” to influence health. As discussed in previous classes, behavioral factors and clinical care are important mechanisms, but study after study has shown that behaviors and medical care cannot fully explain the magnitude of social inequalities in health. In this class we will review key hypothesized mechanisms via which adverse social experiences change human physiology and have enduring effects on long term health outcomes. Leading hypotheses include the role of epigenetic changes; dysregulation of stress responses via hypothalamic pituitary adrenal axis alterations; and physiologic triggers of behavioral patterns. We will discuss how these biological mechanisms directly relate to lifecourse models for the determinants of adult health. We will also discuss controversial perspectives on the role of genetic differences in creating social and racial inequalities in health.
Faculty: Kaja LeWinn
Location (Access restricted to registered students): Zoom URL-
Watch -Live Lecture Media Resource
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Kuzawa et al-2009-American Journal of Human Biology File
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Forrester Stress File
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McCrory SEP File
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MESA epigenetics File
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Homework Help
Location (Access restricted to registered students): Zoom URL
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Lecture: Bringing it together: Applying the socioecological model in clinical and translational research
An understanding of the multi-level influences on health and health disparities can improve the quality and impact of clinical and translational research. By applying an understanding of the impact of the social determinants of health and racism on health, researchers can optimize how they select research questions, apply research methods and analytic approaches to these question, and interpret these findings. In this session we will discuss approaches to accomplishing these goals, including the measurement of socioeconomic status and race, the inclusion of these factors in analytic models, and strategies to optimize recruitment and retention of diverse populations in research studies.
Faculty: Christine Dehlendorf
Location (Access restricted to registered students): Zoom URL-
Watch -Live Lecture Media Resource
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Lecture - Please review before Feb. 2 Media Resource
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Braveman Socioeconomic Status File
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caulfield race File
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Quinn SC 2012 Attributes of researchers File
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Bidil BibbinsDomingo File
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Prather SEM File
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jama goodman 2021 vp 200257 1611350536.05739 File
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Mersha Race File
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Chambers2021 Article BlackWomenSPerspectivesOnStruc (1) File
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Homework Help
Location (Access restricted to registered students): Zoom URL
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Lecture: Multi-level etiologies of health in diverse populations, Part 5: Social policy
Many policies regulating areas such as housing, income security, education, criminal justice, environmental safety, or discrimination strongly influence health and health disparities, even though health was not the primary or original focus of these policies. In other words, the most important policies affecting health may not be health policies at all, but rather policies that shape the multilevel determinants of health. Health researchers with multilevel frameworks are rapidly focusing research attention to formally evaluate how these policies influence health and health inequalities and provide evidence to policymakers about unanticipated health consequences of diverse policies. In this class we will discuss examples of such policies and approaches to rigorously evaluating the health impacts of policies.
Faculty: Rita Hamad
Location (Access restricted to registered students): Zoom URL
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Watch -Live Lecture Media Resource
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Collin 2020 - Short-term effects of EITC on mental health and health behaviors File
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Homework Help
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Lecture: Basic measurement issues in health disparities research
How do we describe the magnitude of health disparities, or decide whether health disparities are getting smaller or larger? Although it may sound simple, there are many different approaches to quantifying disparities, and sometimes they give very different insights. In this class we will compare some approaches, such as focusing on absolute versus relative inequalities and how to choose a reference category. We will also address some basic concepts in measurement of variables in health disparities research. Rigorous, reproducible measurement protocols are essential to scientific progress, but many key variables in health disparities research are controversial to define or difficult to measure, such as segregation, racism, or social capital. We will discuss some strategies to overcoming these measurement challenges and to give health disparities research a strong scientific grounding.
Faculty: Patience Afulani
Location (Access restricted to registered students): Zoom URL-
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Krieger EverydayDiscrimination File
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Stewart- Can we afford to ignore measurement File
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Measures Epi File
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Atkins Racism File
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discrimination resource dec. 2020 File
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Afulani et al-2017-Kenya validation File
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Keppel Measurement File
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Homework Help
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Lecture: Basic analytic issues in HDR
Given the complex social and biologic context in which health disparities are manifested, research in this areas requires nuanced application of statistical concepts related to confounding, mediation, moderation, and clustering. In this lecture, we will highlight aspects of statistical analysis of particular relevance to health disparities, including how to quantify disparities and evaluate determinants of inequalities, how to best build multivariate models, how to investigate race/SES interactions, principles of sub-group reporting and statistical power in health disparities research, as well as an overview of multilevel analyses.
Faculty: Anusha M Vable
Location (Access restricted to registered students): Zoom URL-
Watch -Live Lecture Media Resource
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Victora CG et al. The Role of Conceptual Frameworks in Epidemiological Analysis: A Hierarchical Approach. International Journal of Epidemiology. Voll. 26. No.1 1997 File
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Vable AM et al. Do the health benefits of education vary by sociodemographic subgroup? Differential returns to education and implications for health inequities. Annals of Epidemiology Vol 28 pg. 759-766. 2018 File
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Diez-Roux, AV. Bringing Context Back into Epidemiology: Variables and Fallacies in Multilevel Analysis. American Journal of Public Health. Vol. 88, No. 2. 1998 File
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Lorch SA et al. Factors That Mediate Racial/Ethnic Disparities in US Fetal Death Rates. American Journal of Phublic Health. Vol 102, No.10. October 2012 File
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Coley SL. Does Neighborhood Risk Explain Racial Disparities in Low Birth Weight among Infants Born to Adolescent Mothers? J Pediatr Adolesc Gynecol. 2016 April ; 29(2): 122–129. File
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Merlo J et al. A brief conceptual tutorial of multilevel analysis in social epidemiology: linking the statistical concept of clustering to the idea of contextual phenomenon. J Epidemiol Community Health 2005;59:443–449 File
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Kawachi, I and Subramanian SV. Measuring and Modeling the Social and Geographic Context of Trauma: A Multilevel Modeling Approach. Journal of Traumatic Stress. Vol. 19, No. 2. 2006 File
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Homework Help
Location (Access restricted to registered students): Zoom URL
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Lecture: Strategic science in health disparities research
Doing research that has an impact on our understanding of and ability to address health disparities requires being strategic about what research questions to ask and how to disseminate the results. This lecture will provide guidance on how to ensure your research has the greatest possible impact, including discussions of how to do research that is policy relevant, how to communicate one’s results to the media and public, and how to translate research results into policy.
Faculty: Kirsten Bibbins-Domingo
Location (Access restricted to registered students): Zoom URL
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Watch -Live Lecture Media Resource
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Gollust AJPH Dec 2009 polarizing effects of news msgs re SDOH File
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socially responsible science.NATURE File
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BIDIL.ANNALs.BibbinsDomingo File
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Winett et al AJPH Mommy Blame 2016 (1) (002) File
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Homework Help
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Lecture: Doing research to reduce health disparities
While all health disparities research has a common goal of addressing pervasive and unjust differences in health outcomes, the research methods that can be employed to accomplish this goal are diverse. In this lecture, we will review the “three generations” of health disparities research – from description to intervention – and discuss toolbox of research approaches that can be used to answer questions relevant to health disparities across these generations, including qualitative methods, implementation research, patient-centered outcomes research, and community based participatory research.
Faculty: Christine Dehlendorf
Location (Access restricted to registered students): Zoom URL-
Watch -Live Lecture Media Resource
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barbershop File
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annurev-publhealth-031210-101136 File
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poi160066 (1) File
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Walton intervention File
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cliff-analogy File
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Homework Help
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Lecture: Student presentation
Each of you will give a short presentation to share with us something about how the material in this class has or will inform your work. This can really be anything, but examples would include application of the socioecological model to your area of research, measurement or analytic issues, and how to think strategically about your area of research.
Each presenter will have 5-8 minutes, with a few minutes for questions, so you should only prepare 3-5 slides. In addition to this presentation, the final project will be a brief 1 page summary of what you will discuss in your presentation..
Please send me your slides by midnight on Monday, March 15th so I can compile them all and we can be as efficient as possible (my email is christine.dehlendorf@ucsf.edu).
Faculty: Christine Dehlendorf and Ellie Matthay
Location (Access restricted to registered students): Zoom URL
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Watch Michelle Section 03.16.2021 Media Resource
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Watch C.Dehlendorf Section 03.16.2021 Media Resource
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Watch S.McKenzie-Sampson Section 03.16.2021 Media Resource
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PHCRP SSM File
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Ford PHCRP File
